SCHEMBL17433767

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17145459	0.83	AHR (0.50)	TP53PDE4BMAPTPOLBGAA
	SCHEMBL29375452	0.83	AHR (0.50)	TP53PDE4BMAPTPOLBGAA
	SCHEMBL17433795	0.82	KDM4E (0.52)	BACE1HSD17B10NCF1CYBBNOX5
	SCHEMBL17433765	0.82	BACE1 (0.47)	BACE1TP53HSD17B10NCF1GABRP
	SCHEMBL14113741	0.81	ALDH1A1 (0.50)	TP53HSD17B10PDE4BMAPTPOLB
	SCHEMBL17434143	0.79	BACE1 (0.56)	BACE1TP53HSD17B10NCF1KMT2A
	SCHEMBL13447998	0.77	PARP1 (0.48)	TP53PDE4BMAPTPOLBGAA
	SCHEMBL17433794	0.75	KMT2A (0.54)	BACE1MAPTPOLBGAAKMT2A
	SCHEMBL28158670	0.74	PLAU (0.55)	BACE1NCF1PLAU
	SCHEMBL13040660	0.73	NCF1 (0.46)	NCF1PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.