SCHEMBL17434808

SCHEMBL17434808

C=CC(=O)Oc1ccc2ccc3c(c2c1)N=CC1(O3)N(C)c2ccccc2C1(C)C

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.75
LMNA P02545 6/20 0.75
THRB P10828 5/20 0.75
KDM4E B2RXH2 5/20 0.75
SMN1; SMN2 Q16637 4/20 0.75
HTT P42858 4/20 0.75
GAA P10253 4/20 0.75
ALDH1A1 P00352 3/20 0.75
HPGD P15428 3/20 0.75
RECQL P46063 3/20 0.75
TDP1 Q9NUW8 3/20 0.75
ALOX12 P18054 2/20 0.75
L3MBTL1 Q9Y468 2/20 0.75
POLB P06746 2/20 0.75
MAPK1 P28482 2/20 0.75
PKM P14618 2/20 0.66
NPSR1 Q6W5P4 3/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20757413 0.92 MAPT (0.79) MAPTLMNATHRBKDM4ESMN1; SMN2
SCHEMBL17434806 0.90 MAPT (0.61) MAPTLMNATHRBKDM4ESMN1; SMN2
SCHEMBL30920073 0.90 MAPT (0.61) MAPTLMNATHRBKDM4ESMN1; SMN2
SCHEMBL31094046 0.90 MAPT (0.73) MAPTLMNATHRBKDM4ESMN1; SMN2
SCHEMBL4252905 0.90 MAPT (0.73) MAPTLMNATHRBKDM4ESMN1; SMN2
SCHEMBL12813570 0.89 MAPT (0.74) MAPTLMNATHRBKDM4ESMN1; SMN2
SCHEMBL12812592 0.89 MAPT (0.74) MAPTLMNATHRBKDM4ESMN1; SMN2
SCHEMBL9912585 0.89 MAPT (0.74) MAPTLMNATHRBKDM4ESMN1; SMN2
SCHEMBL13874056 0.89 MAPT (0.74) MAPTLMNATHRBKDM4ESMN1; SMN2
SCHEMBL13874044 0.87 MAPT (0.71) MAPTLMNATHRBKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3169235-B1 DEVICE FOR MEASURING THE CONCENTRATION OF AN ANALYTE IN THE BLOOD OR TISSUE OF AN ANIMAL OR A HUMAN, PARTICULARLY A PREMATURE INFANT, IN A SELF-CALIBRATING MANNER UNIV ZUERICH (CH) 2024-05-22 EP disclosed
US-11006866-B2 Device for measuring the concentration of an analyte in the blood or tissue of an animal or a human, particularly a premature infant, in a self-calibrating manner UNIVERSITAT ZURICH (CH) 2021-05-18 US disclosed
US-20170202492-A1 DEVICE FOR MEASURING THE CONCENTRATION OF AN ANALYTE IN THE BLOOD OR TISSUE OF AN ANIMAL OR A HUMAN, PARTICULARLY A PREMATURE INFANT, IN A SELF-CALIBRATING MANNER UNIVERSITAT ZURICH (CH) 2017-07-20 US disclosed
EP-2974656-A1 Device for measuring the concentration of an analyte in the blood or tissue of an animal or a human, particularly a premature infant, in a self-calibrating manner Universität Zürich (CH) 2016-01-20 EP disclosed