SCHEMBL4252905

SCHEMBL4252905

C=C(C)C(=O)Oc1ccc2ccc3c(c2c1)N=CC1(O3)N(C)c2ccccc2C1(C)C

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.73
LMNA P02545 6/20 0.73
THRB P10828 5/20 0.73
KDM4E B2RXH2 5/20 0.73
SMN1; SMN2 Q16637 4/20 0.73
HTT P42858 4/20 0.73
GAA P10253 4/20 0.73
ALDH1A1 P00352 3/20 0.73
HPGD P15428 3/20 0.73
RECQL P46063 3/20 0.73
TDP1 Q9NUW8 3/20 0.73
ALOX12 P18054 2/20 0.73
L3MBTL1 Q9Y468 2/20 0.73
POLB P06746 2/20 0.73
MAPK1 P28482 2/20 0.73
PKM P14618 2/20 0.64
NPSR1 Q6W5P4 3/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31094046 1.00 MAPT (0.73) MAPTLMNATHRBKDM4ESMN1; SMN2
SCHEMBL20757413 0.92 MAPT (0.79) MAPTLMNATHRBKDM4ESMN1; SMN2
SCHEMBL17434808 0.90 MAPT (0.75) MAPTLMNATHRBKDM4ESMN1; SMN2
SCHEMBL9220377 0.89 MAPT (0.58) MAPTLMNATHRBKDM4ESMN1; SMN2
SCHEMBL31094041 0.89 MAPT (0.58) MAPTLMNATHRBKDM4ESMN1; SMN2
SCHEMBL13659168 0.89 MAPT (0.62) MAPTLMNATHRBKDM4ESMN1; SMN2
SCHEMBL13874056 0.87 MAPT (0.74) MAPTLMNATHRBKDM4ESMN1; SMN2
SCHEMBL9912585 0.87 MAPT (0.74) MAPTLMNATHRBKDM4ESMN1; SMN2
SCHEMBL12812592 0.87 MAPT (0.74) MAPTLMNATHRBKDM4ESMN1; SMN2
SCHEMBL12813570 0.87 MAPT (0.74) MAPTLMNATHRBKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3169235-B1 DEVICE FOR MEASURING THE CONCENTRATION OF AN ANALYTE IN THE BLOOD OR TISSUE OF AN ANIMAL OR A HUMAN, PARTICULARLY A PREMATURE INFANT, IN A SELF-CALIBRATING MANNER UNIV ZUERICH (CH) 2024-05-22 EP disclosed
US-11006866-B2 Device for measuring the concentration of an analyte in the blood or tissue of an animal or a human, particularly a premature infant, in a self-calibrating manner UNIVERSITAT ZURICH (CH) 2021-05-18 US disclosed
US-20170202492-A1 DEVICE FOR MEASURING THE CONCENTRATION OF AN ANALYTE IN THE BLOOD OR TISSUE OF AN ANIMAL OR A HUMAN, PARTICULARLY A PREMATURE INFANT, IN A SELF-CALIBRATING MANNER UNIVERSITAT ZURICH (CH) 2017-07-20 US disclosed
EP-2974656-A1 Device for measuring the concentration of an analyte in the blood or tissue of an animal or a human, particularly a premature infant, in a self-calibrating manner Universität Zürich (CH) 2016-01-20 EP disclosed
WO-2009121148-A1 DYE COMPRISING FUNCTIONAL SUBSTITUENT ADVANCED POLYMERIK PTY LTD (AU) 2009-10-08 WO disclosed
WO-2009121148-A1 DYE COMPRISING FUNCTIONAL SUBSTITUENT ADVANCED POLYMERIK PTY LTD (AU) 2009-10-08 WO disclosed
US-20070249794-A1 Photochromic Compositions and Articles Comprising Polyether Oligomer POLYMERS AUSTRALIA PTY LIMITED (AU) 2007-10-25 US disclosed
US-20070249794-A1 Photochromic Compositions and Articles Comprising Polyether Oligomer POLYMERS AUSTRALIA PTY LIMITED (AU) 2007-10-25 US disclosed
EP-0277639-B1 Photochromic compound TORAY INDUSTRIES (JP) 1995-01-25 EP disclosed
US-5166345-A Spirooxazine polymerizable compounds TORAY INDUSTRIES, INC. (JP) 1992-11-24 US disclosed
US-4929693-A CONTACT LENSES, WEATHERPROOFING TORAY INDUSTRIES, INC. (JP) 1990-05-29 US disclosed