Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 11/20 | 0.38 |
| ▸ | GSK3B | P49841 | 9/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 9/20 | 0.36 |
| ▸ | WNT1 | P04628 | 8/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17435143 | 0.88 | IL2 (0.39) | IL2 | |
| SCHEMBL17435144 | 0.87 | IL2 (0.38) | IL2GSK3BDYRK1AWNT1 | |
| SCHEMBL15214060 | 0.85 | IL2 (0.43) | IL2GSK3BDYRK1AWNT1 | |
| SCHEMBL17435148 | 0.83 | IL2 (0.40) | IL2 | |
| SCHEMBL17435134 | 0.83 | IL2 (0.40) | IL2 | |
| SCHEMBL17435136 | 0.82 | IL2 (0.42) | IL2 | |
| SCHEMBL17435133 | 0.82 | IL2 (0.40) | IL2 | |
| SCHEMBL17435138 | 0.82 | IL2 (0.39) | IL2GSK3BDYRK1AWNT1 | |
| SCHEMBL5550547 | 0.76 | IL2 (0.63) | IL2GSK3BDYRK1AWNT1 | |
| SCHEMBL5554309 | 0.76 | IL2 (0.53) | IL2GSK3BDYRK1AWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848435-B1 | COMPOUNDS AGAINST INFLAMMATIONS AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP (US) | 2016-01-20 | — | — | EP | claimed |