Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 12/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 4/20 | 0.35 |
| ▸ | BRAF | P15056 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17435132 | 0.92 | IL2 (0.35) | IL2CREBBPTSHRMEN1NPC1 | |
| SCHEMBL17435136 | 0.88 | IL2 (0.42) | IL2 | |
| SCHEMBL17435138 | 0.86 | IL2 (0.39) | IL2 | |
| SCHEMBL15214059 | 0.85 | IL2 (0.46) | IL2CREBBPRAF1BRAFUSP2 | |
| SCHEMBL17435124 | 0.83 | IL2 (0.38) | IL2 | |
| SCHEMBL17435133 | 0.83 | IL2 (0.40) | IL2 | |
| SCHEMBL17435144 | 0.82 | IL2 (0.38) | IL2 | |
| SCHEMBL17435134 | 0.82 | IL2 (0.40) | IL2LMNAMAPT | |
| SCHEMBL17435143 | 0.82 | IL2 (0.39) | IL2 | |
| SCHEMBL17435142 | 0.80 | IL2 (0.36) | IL2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848435-B1 | COMPOUNDS AGAINST INFLAMMATIONS AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP (US) | 2016-01-20 | — | — | EP | claimed |