Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 13/20 | 0.42 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.33 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17435142 | 0.92 | IL2 (0.36) | IL2MAP4K1PORCNWNT3APIK3C3 | |
| SCHEMBL14562873 | 0.90 | IL2 (0.42) | IL2MAP4K1PORCNPIK3CDPIK3CG | |
| SCHEMBL17435148 | 0.88 | IL2 (0.40) | IL2 | |
| SCHEMBL8259711 | 0.85 | IL2 (0.46) | IL2MAP4K1 | |
| SCHEMBL17435133 | 0.84 | IL2 (0.40) | IL2PORCNPIK3CDPIK3CG | |
| SCHEMBL17435138 | 0.84 | IL2 (0.39) | IL2 | |
| SCHEMBL17435134 | 0.84 | IL2 (0.40) | IL2PORCNWNT3A | |
| SCHEMBL17435143 | 0.83 | IL2 (0.39) | IL2PORCNWNT3A | |
| SCHEMBL14562874 | 0.83 | PORCN (0.39) | IL2MAP4K1PORCNPIK3C3 | |
| SCHEMBL17435144 | 0.82 | IL2 (0.38) | IL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848435-B1 | COMPOUNDS AGAINST INFLAMMATIONS AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP (US) | 2016-01-20 | — | — | EP | claimed |