Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL733456 | 0.96 | MEN1 (0.33) | MEN1KMT2ATDP1 | |
| SCHEMBL8575584 | 0.96 | MEN1 (0.33) | MEN1KMT2ATDP1 | |
| SCHEMBL720011 | 0.96 | MEN1 (0.33) | MEN1KMT2ATDP1 | |
| SCHEMBL8568331 | 0.96 | MEN1 (0.33) | MEN1KMT2ATDP1 | |
| SCHEMBL104139 | 0.96 | MEN1 (0.33) | MEN1KMT2ATDP1 | |
| SCHEMBL8573056 | 0.96 | MEN1 (0.33) | MEN1KMT2ATDP1 | |
| SCHEMBL8565493 | 0.96 | MEN1 (0.33) | MEN1KMT2ATDP1 | |
| SCHEMBL8569527 | 0.96 | MEN1 (0.33) | MEN1KMT2ATDP1 | |
| SCHEMBL8566528 | 0.96 | MEN1 (0.33) | MEN1KMT2ATDP1 | |
| SCHEMBL8569445 | 0.96 | MEN1 (0.33) | MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2923692-B1 | Beta-amino ester compounds and uses thereof | LIVING PROOF INC (US) | 2018-05-30 | — | — | EP | claimed |
| EP-2923692-A1 | Beta-amino ester compounds and uses thereof | Living Proof, Inc. (US) | 2015-09-30 | — | — | EP | claimed |
| US-20160002406-A1 | BETA-AMINO ESTER COMPOUNDS AND USES THEREOF | LIVING PROOF, INC. (US) | 2016-01-07 | — | — | US | disclosed |
| US-9175114-B2 | Beta-amino ester compounds and uses thereof | LIVING PROOF, INC. (US) | 2015-11-03 | — | — | US | disclosed |
| EP-2923692-A1 | Beta-amino ester compounds and uses thereof | Living Proof, Inc. (US) | 2015-09-30 | — | — | EP | disclosed |
| EP-2387386-B1 | BETA-AMINO ESTER COMPOUNDS AND USES THEREOF | LIVING PROOF INC (US) | 2015-03-18 | — | — | EP | disclosed |
| US-20140256885-A1 | BETA-AMINO ESTER COMPOUNDS AND USES THEREOF | LIVING PROOF, INC. (US) | 2014-09-11 | — | — | US | disclosed |
| US-8748551-B2 | β-amino ester compounds and uses thereof | LIVING PROOF, INC. (US) | 2014-06-10 | — | — | US | disclosed |
| US-20130121947-A1 | BETA-AMINO ESTER COMPOUNDS AND USES THEREOF | LIVING PROOF, INC. (US) | 2013-05-16 | — | — | US | disclosed |
| US-8362175-B2 | Beta-amino ester compounds and uses thereof | LIVING PROOF, INC. (US) | 2013-01-29 | — | — | US | disclosed |
| US-20120164095-A1 | BETA-AMINO ESTER COMPOUNDS AND USES THEREOF | LIVING PROOF, INC. (US) | 2012-06-28 | — | — | US | disclosed |
| US-8163861-B2 | Beta-amino ester compounds and uses thereof | LIVING PROOF, INC. (US) | 2012-04-24 | — | — | US | disclosed |
| EP-2387386-A2 | BETA-AMINO ESTER COMPOUNDS AND USES THEREOF | Living Proof, Inc. (US) | 2011-11-23 | — | — | EP | disclosed |
| US-8040383-B2 | Communication system, communication method, computer-readable medium and image shooting device | FUJIFILM CORPORATION (JP) | 2011-10-18 | — | — | US | disclosed |
| WO-2010083379-A2 | BETA-AMINO ESTER COMPOUNDS AND USES THEREOF | LIVING PROOF, INC. (US) | 2010-07-22 | — | — | WO | disclosed |
| US-20100178267-A1 | BETA-AMINO ESTER COMPOUNDS AND USES THEREOF | LIVING PROOF, INC. (US) | 2010-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120164095-A1 | BETA-AMINO ESTER COMPOUNDS AND USES THEREOF | AADAT, BCAT2, EBP | MEN1 1463/4885KMT2A 1046/4885TDP1 1065/4885 |
| US-20160002406-A1 | BETA-AMINO ESTER COMPOUNDS AND USES THEREOF | AADAT, BCAT2, EBP | MEN1 1463/4885KMT2A 1046/4885TDP1 1065/4885 |
| US-20100178267-A1 | BETA-AMINO ESTER COMPOUNDS AND USES THEREOF | AADAT, BCAT2, EBP | MEN1 1463/4885KMT2A 1046/4885TDP1 1065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.