SCHEMBL17435653

SCHEMBL17435653

C=CC1CCC(OCC(C)C)C(O)C1

nearest known ligand 0.30

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30
CTSV O60911 1/20 0.30
CTSL P07711 1/20 0.30
CTSB P07858 1/20 0.30
CTSS P25774 1/20 0.30
CTSK P43235 1/20 0.30
CTSC P53634 1/20 0.30
CTSF Q9UBX1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17435651 0.87 TSHR (0.30) TSHRCTSVCTSLCTSBCTSS
SCHEMBL17435470 0.81 ALDH1A1 (0.31)
SCHEMBL17435755 0.80
SCHEMBL17435476 0.79 GBA1 (0.30)
SCHEMBL17435484 0.78
SCHEMBL20169774 0.76
SCHEMBL17435467 0.76 GBA1 (0.38) TSHR
SCHEMBL17435392 0.75
SCHEMBL17435541 0.74 CHRM2 (0.36)
SCHEMBL17435416 0.73 MAPK14 (0.33) CTSVCTSLCTSBCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105272833-B Novel cyclohexanols and their use in perfuming compositions 国际香料和香精公司 2020-09-22 CN disclosed
US-9975835-B2 Cyclohexanols and their use in perfume compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2018-05-22 US disclosed
US-9975835-B2 Cyclohexanols and their use in perfume compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2018-05-22 US disclosed
US-9975835-B2 Cyclohexanols and their use in perfume compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2018-05-22 US disclosed
US-9834500-B2 Cyclohexanols and their use in perfume compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2017-12-05 US disclosed
US-9834500-B2 Cyclohexanols and their use in perfume compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2017-12-05 US disclosed
US-9834500-B2 Cyclohexanols and their use in perfume compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2017-12-05 US disclosed
EP-2977365-B1 NOVEL CYCLOHEXANOLS AND THEIR USE IN PERFUME COMPOSITION INT FLAVORS & FRAGRANCES INC (US) 2017-10-18 EP disclosed
EP-2977365-B1 NOVEL CYCLOHEXANOLS AND THEIR USE IN PERFUME COMPOSITION INT FLAVORS & FRAGRANCES INC (US) 2017-10-18 EP disclosed
US-20160332946-A1 NOVEL CYCLOHEXANOLS AND THEIR USE IN PERFUME COMPOSITIONS INT FLAVORS & FRAGRANCES INC (US) 2016-11-17 US disclosed
US-9416334-B2 Cyclohexanols and their use in perfume compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2016-08-16 US disclosed
EP-2977365-A1 NOVEL CYCLOHEXANOLS AND THEIR USE IN PERFUME COMPOSITION International Flavors & Fragrances Inc. (US) 2016-01-27 EP disclosed
EP-2977365-A1 NOVEL CYCLOHEXANOLS AND THEIR USE IN PERFUME COMPOSITION International Flavors & Fragrances Inc. (US) 2016-01-27 EP disclosed
CN-105272833-A Novel cyclohexanols and their use in perfume compositions INT FLAVORS & FRAGRANCES INC 2016-01-27 CN disclosed
US-20160017258-A1 NOVEL CYCLOHEXANOLS AND THEIR USE IN PERFUME COMPOSITIONS INTERNATIONAL FLAVORS & FRAGRANCES INC. 2016-01-21 US disclosed
US-20160016873-A1 NOVEL CYCLOHEXANOLS AND THEIR USE IN PERFUME COMPOSITIONS INTERNATIONAL FLAVORS & FRAGRANCES INC. 2016-01-21 US disclosed
US-20160017258-A1 NOVEL CYCLOHEXANOLS AND THEIR USE IN PERFUME COMPOSITIONS INTERNATIONAL FLAVORS & FRAGRANCES INC. 2016-01-21 US disclosed
US-20160017258-A1 NOVEL CYCLOHEXANOLS AND THEIR USE IN PERFUME COMPOSITIONS INTERNATIONAL FLAVORS & FRAGRANCES INC. 2016-01-21 US disclosed
US-20160016873-A1 NOVEL CYCLOHEXANOLS AND THEIR USE IN PERFUME COMPOSITIONS INTERNATIONAL FLAVORS & FRAGRANCES INC. 2016-01-21 US disclosed
US-20160016873-A1 NOVEL CYCLOHEXANOLS AND THEIR USE IN PERFUME COMPOSITIONS INTERNATIONAL FLAVORS & FRAGRANCES INC. 2016-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160332946-A1 NOVEL CYCLOHEXANOLS AND THEIR USE IN PERFUME COMPOSITIONS TRPA1, C1S, C5 TSHR 4686/4885CTSV 3353/4885CTSL 4212/4885
US-20160016873-A1 NOVEL CYCLOHEXANOLS AND THEIR USE IN PERFUME COMPOSITIONS TRPA1, C1S, C5 TSHR 4686/4885CTSV 3353/4885CTSL 4212/4885
US-20160017258-A1 NOVEL CYCLOHEXANOLS AND THEIR USE IN PERFUME COMPOSITIONS C5, C3AR1, C1S TSHR 4509/4885CTSV 3812/4885CTSL 4102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.