Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346068 | 1.00 | SMN1; SMN2 (0.34) | SMN1; SMN2ALDH1A1MAPTPTGS1CA1 | |
| SCHEMBL17435743 | 1.00 | SMN1; SMN2 (0.34) | SMN1; SMN2ALDH1A1MAPTPTGS1CA1 | |
| SCHEMBL10080777 | 0.78 | CA1 (0.36) | SMN1; SMN2CA1CA2 | |
| SCHEMBL500459 | 0.77 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1MAPTPTGS1CA1 | |
| SCHEMBL20879474 | 0.77 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1MAPTPTGS1CA1 | |
| SCHEMBL500460 | 0.77 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1MAPTPTGS1CA1 | |
| SCHEMBL17451851 | 0.76 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1CA1CA2CA14 | |
| SCHEMBL16821022 | 0.75 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1MAPTPTGS1CA1 | |
| Hydrochloric Acid SCHEMBL1705950 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1MAPTPTGS1CA1 | |
| SCHEMBL16147546 | 0.75 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1MAPTPTGS1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170369426-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. | 2017-12-28 | — | — | US | disclosed |
| US-20170369426-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. | 2017-12-28 | — | — | US | disclosed |
| US-9701622-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-07-11 | — | — | US | disclosed |
| US-9701622-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-07-11 | — | — | US | disclosed |
| US-9701622-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-07-11 | — | — | US | disclosed |
| US-20160280639-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. | 2016-09-29 | — | — | US | disclosed |
| US-20160280639-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. | 2016-09-29 | — | — | US | disclosed |
| US-20160280639-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. | 2016-09-29 | — | — | US | disclosed |
| US-9403758-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2016-08-02 | — | — | US | disclosed |
| US-9403758-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2016-08-02 | — | — | US | disclosed |
| US-9403758-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2016-08-02 | — | — | US | disclosed |
| US-20160016895-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. | 2016-01-21 | — | — | US | disclosed |
| US-20160016895-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. | 2016-01-21 | — | — | US | disclosed |
| US-20160016895-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016895-A1 | ANTIBACTERIAL AGENTS | MRPL21, ABCB11, LSS | SMN1; SMN2 1996/4885ALDH1A1 1168/4885MAPT 4489/4885 |
| US-20170369426-A1 | ANTIBACTERIAL AGENTS | MRPL21, ABCB11, LSS | SMN1; SMN2 1996/4885ALDH1A1 1168/4885MAPT 4489/4885 |
| US-20160280639-A1 | ANTIBACTERIAL AGENTS | MRPL21, ABCB11, LSS | SMN1; SMN2 1996/4885ALDH1A1 1168/4885MAPT 4489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.