Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | VDR | P11473 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | UBE2N | P61088 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17436805 | 0.80 | MAPK1 (0.41) | MAPK1SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL9340135 | 0.75 | HCAR2 (0.53) | MAPK1SMN1; SMN2KMT2AALDH1A1NPC1 | |
| SCHEMBL7572645 | 0.75 | MAPK1 (0.42) | MAPK1SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL9853733 | 0.75 | MAPK1 (0.43) | MAPK1SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL11477144 | 0.71 | MAPK1 (0.61) | MAPK1SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL778350 | 0.70 | MAPK1 (0.47) | MAPK1SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL29630093 | 0.70 | MAPK1 (0.47) | MAPK1SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL2677332 | 0.70 | MAPK1 (0.49) | MAPK1SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL27563485 | 0.70 | HDAC1 (0.50) | MAPK1SMN1; SMN2ALDH1A1CYP2C9MAPT | |
| SCHEMBL8189951 | 0.70 | MAPK1 (0.44) | MAPK1SMN1; SMN2MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10308601-B2 | Isothiocyanate production method, composition for transporting and storing N-substituted O-substituted thiocarbamate, and isothiocyanate composition | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2019-06-04 | — | — | US | disclosed |
| US-20160016901-A1 | ISOTHIOCYANATE PRODUCTION METHOD, COMPOSITION FOR TRANSPORTING AND STORING N-SUBSTITUTED O-SUBSTITUTED THIOCARBAMATE, AND ISOTHIOCYANATE COMPOSITION | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016901-A1 | ISOTHIOCYANATE PRODUCTION METHOD, COMPOSITION FOR TRANSPORTING AND STORING N-SUBSTITUTED O-SUBSTITUTED THIOCARBAMATE, AND ISOTHIOCYANATE COMPOSITION | TST, SLCO4C1, SLCO2B1 | MAPK1 4335/4885SMN1; SMN2 4351/4885MEN1 3988/4885 |
| US-10308601-B2 | Isothiocyanate production method, composition for transporting and storing N-substituted O-substituted thiocarbamate, and isothiocyanate composition | TST, SLCO4C1, SLCO2B1 | MAPK1 4335/4885SMN1; SMN2 4351/4885MEN1 3988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.