SCHEMBL9853733

SCHEMBL9853733

CCC(C)(C)c1ccc(NC=O)c(C(C)(C)CC)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 7/20 0.43
NPSR1 Q6W5P4 6/20 0.43
MAPT P10636 6/20 0.43
SMN1; SMN2 Q16637 5/20 0.42
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
ALDH1A1 P00352 1/20 0.42
RAB9A P51151 4/20 0.41
NPC1 O15118 3/20 0.41
LMNA P02545 1/20 0.41
CASP3 P42574 1/20 0.41
ATM Q13315 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
HTT P42858 3/20 0.36
UBE2N P61088 2/20 0.36
GLA P06280 1/20 0.36
MITF O75030 1/20 0.36
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7572645 0.77 MAPK1 (0.42) MAPK1NPSR1MAPTSMN1; SMN2MEN1
SCHEMBL11048618 0.76 MAPK1 (0.55) MAPK1NPSR1MAPTMEN1KMT2A
SCHEMBL17436804 0.75 MAPK1 (0.46) MAPK1NPSR1MAPTSMN1; SMN2MEN1
SCHEMBL22519823 0.74 ALDH1A1 (0.43) MAPK1NPSR1MAPTSMN1; SMN2KMT2A
SCHEMBL17436805 0.73 MAPK1 (0.41) MAPK1NPSR1MAPTSMN1; SMN2MEN1
SCHEMBL19498229 0.73 MAPT (0.36) MAPK1NPSR1MAPTSMN1; SMN2GLA
SCHEMBL778350 0.73 MAPK1 (0.47) MAPK1NPSR1MAPTSMN1; SMN2MEN1
SCHEMBL29630093 0.73 MAPK1 (0.47) MAPK1NPSR1MAPTSMN1; SMN2MEN1
SCHEMBL20371850 0.72 ALDH1A1 (0.42) MAPK1NPSR1MAPTSMN1; SMN2MEN1
SCHEMBL7240794 0.72 MAPK1 (0.59) MAPK1NPSR1MAPTSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0456163-A2 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1991-11-13 EP disclosed