Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17437403 | 0.81 | RAB9A (0.32) | POLB | |
| SCHEMBL3178005 | 0.71 | NPC1 (0.34) | ALDH1A1MAPTHSD17B10KMT2AGAA | |
| SCHEMBL4421719 | 0.69 | ALDH1A1 (0.56) | ALDH1A1MAPTHSD17B10KMT2ALMNA | |
| SCHEMBL3756193 | 0.68 | KDM4E (0.32) | ALDH1A1LMNATSHRKDM4E | |
| SCHEMBL4250864 | 0.67 | PDPK1 (0.38) | ALDH1A1MAPTHSD17B10KMT2AL3MBTL1 | |
| SCHEMBL17437377 | 0.66 | MAPT (0.71) | ALDH1A1MAPTHSD17B10KMT2AL3MBTL1 | |
| SCHEMBL4638534 | 0.66 | — | — | |
| SCHEMBL4250094 | 0.63 | DYRK1A (0.48) | MAPTSMN1; SMN2 | |
| SCHEMBL3752317 | 0.62 | HTR2C (0.39) | ALDH1A1MAPTKMT2ALMNAPOLB | |
| SCHEMBL3750058 | 0.61 | PARP14 (0.34) | ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9421193-B2 | Benzothiazole derivatives and a use thereof for the treatment of cancer | KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES (KR) | 2016-08-23 | — | — | US | claimed |
| US-20160120851-A1 | BENZOTHIAZOLE DERIVATIVES AND A USE THEREOF FOR THE TREATMENT OF CANCER | KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES (KR) | 2016-05-05 | — | — | US | claimed |
| US-9266875-B2 | Benzothiazole derivatives and a use thereof for the treatment of cancer | KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES (KR) | 2016-02-23 | — | — | US | claimed |
| US-20160016943-A1 | BENZOTHIAZOLE DERIVATIVES AND A USE THEREOF FOR THE TREATMENT OF CANCER | KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES (KR) | 2016-01-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016943-A1 | BENZOTHIAZOLE DERIVATIVES AND A USE THEREOF FOR THE TREATMENT OF CANCER | SULT1E1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, WEE1 | ALDH1A1 110/4885MAPT 2780/4885HSD17B10 212/4885 |
| US-20160120851-A1 | BENZOTHIAZOLE DERIVATIVES AND A USE THEREOF FOR THE TREATMENT OF CANCER | SULT1E1, CBR3, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | ALDH1A1 96/4885MAPT 2774/4885HSD17B10 224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.