Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 2/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | FNTA | P49354 | 4/20 | 0.41 |
| ▸ | FNTB | P49356 | 4/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ICMT | O60725 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10208287 | 1.00 | POLB (0.44) | POLBANPEPMMELMNAFNTA | |
| SCHEMBL721114 | 0.88 | LMNA (0.42) | LMNAFNTAFNTBGAA | |
| SCHEMBL10208291 | 0.87 | BTN3A1 (0.36) | LMNAFNTAFNTBALDH1A1GAA | |
| SCHEMBL721443 | 0.85 | KMT2A (0.38) | ANPEPLMNAFNTAFNTB | |
| SCHEMBL15726979 | 0.83 | ALDH1A1 (0.42) | LMNACASP1ALDH1A1GAAMAPT | |
| SCHEMBL29708059 | 0.83 | ALDH1A1 (0.42) | LMNACASP1ALDH1A1GAAMAPT | |
| SCHEMBL1744521 | 0.83 | ALDH1A1 (0.42) | LMNACASP1ALDH1A1GAAMAPT | |
| SCHEMBL1743237 | 0.83 | ALDH1A1 (0.42) | LMNACASP1ALDH1A1GAAMAPT | |
| SCHEMBL20305851 | 0.81 | ELANE (0.41) | LMNACASP1ALDH1A1GAAMAPT | |
| SCHEMBL10208224 | 0.81 | ELANE (0.41) | LMNACASP1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385951-A2 | PHOSPHORAMIDATE DERIVATIVES OF GUANOSINE NUCLEOSIDE COMPOUNDS FOR TREATMENT OF VIRAL INFECTIONS | University College Cardiff Consultants, Ltd. (GB) | 2011-11-16 | — | — | EP | disclosed |
| US-20110254856-A1 | MOBILE TERMINAL AND METHOD OF CONTROLLING OPERATION OF THE MOBILE TERMINAL | LG ELECTRONICS INC. (KR) | 2011-10-20 | — | — | US | disclosed |
| WO-2010081082-A2 | PHOSPHORAMIDATE DERIVATIVES OF GUANOSINE NUCLEOSIDE COMPOUNDS FOR TREATMENT OF VIRAL INFECTIONS | UNIVERSITY COLLEGE OF CARDIFF CONSULTANTS LIMITED (GB) | 2010-07-15 | — | — | WO | disclosed |