Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24163472 | 0.86 | ALDH1A1 (0.41) | L3MBTL1RXFP1MAPTKDM4EKMT2A | |
| SCHEMBL1744654 | 0.83 | MAPT (0.32) | L3MBTL1RXFP1MAPTKDM4EKMT2A | |
| SCHEMBL19761072 | 0.71 | L3MBTL1 (0.44) | L3MBTL1RXFP1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL16439309 | 0.68 | L3MBTL1 (0.42) | L3MBTL1RXFP1MAPTKDM4ENPC1 | |
| SCHEMBL1745767 | 0.68 | MAPT (0.35) | L3MBTL1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL31599851 | 0.68 | NPC1 (0.31) | L3MBTL1MAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL31732188 | 0.68 | HAVCR2 (0.33) | L3MBTL1RXFP1 | |
| SCHEMBL19630162 | 0.68 | — | — | |
| SCHEMBL1744572 | 0.68 | CSNK1E (0.38) | — | |
| SCHEMBL16439355 | 0.66 | L3MBTL1 (0.40) | L3MBTL1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385946-A1 | DERIVATIVES OF 6-CYCLOAMINO-2,3-DI-PYRIDINYL-IMIDAZO[1,2-B]-PYRIDAZINE, PREPARATION AND TUERAPEUTIC APPLICATION THEREOF | SANOFI (FR) | 2011-11-16 | — | — | EP | disclosed |
| US-8040450-B2 | Liquid crystal electro-optic device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2011-10-18 | — | — | US | disclosed |
| WO-2010070238-A1 | DERIVATIVES OF 6-CYCLOAMINO-2,3-DI-PYRIDINYL-IMIDAZO[1,2-B]-PYRIDAZINE, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | SANOFI-AVENTIS (FR) | 2010-06-24 | — | — | WO | disclosed |