Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17445737 | 1.00 | THRB (0.59) | THRBLMNAMAPTGBA1 | |
| SCHEMBL15391171 | 0.85 | THRB (0.32) | THRBLMNA | |
| SCHEMBL19011892 | 0.85 | THRB (0.32) | THRBLMNA | |
| SCHEMBL19011757 | 0.85 | THRB (0.32) | THRBLMNA | |
| SCHEMBL803397 | 0.85 | THRB (0.32) | THRBLMNA | |
| SCHEMBL804256 | 0.85 | THRB (0.32) | THRBLMNA | |
| SCHEMBL15391925 | 0.85 | THRB (0.32) | THRBLMNA | |
| SCHEMBL804253 | 0.85 | THRB (0.32) | THRBLMNA | |
| Isosorbide SCHEMBL31538807 | 0.80 | THRB (0.93) | THRBLMNAMAPT | |
| Isosorbide SCHEMBL24465084 | 0.77 | THRB (1.00) | THRBLMNAMAPTGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160016969-A1 | ISOHEXIDE MONOTRIFLATES AND PROCESS FOR SYNTHESIS THEREOF | ARCHER DANIELS MIDLAND COMPANY (US) | 2016-01-21 | — | — | US | disclosed |
| US-20160016969-A1 | ISOHEXIDE MONOTRIFLATES AND PROCESS FOR SYNTHESIS THEREOF | ARCHER DANIELS MIDLAND COMPANY (US) | 2016-01-21 | — | — | US | disclosed |
| US-20160016969-A1 | ISOHEXIDE MONOTRIFLATES AND PROCESS FOR SYNTHESIS THEREOF | ARCHER DANIELS MIDLAND COMPANY (US) | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016969-A1 | ISOHEXIDE MONOTRIFLATES AND PROCESS FOR SYNTHESIS THEREOF | PPIP5K2, TALDO1, MSH2 | THRB 3354/4885LMNA 1370/4885MAPT 2573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.