Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL28214997 | 0.83 | ALDH1A1 (0.61) | ALDH1A1MAPTLMNAGAARAB9A | |
| Quinoline SCHEMBL9110133 | 0.79 | ALDH1A1 (0.66) | ALDH1A1MAPTGAARAB9ANPC1 | |
| Quinoline SCHEMBL28125811 | 0.79 | ALDH1A1 (0.57) | ALDH1A1MAPTLMNARAB9ANPC1 | |
| SCHEMBL439543 | 0.78 | CA1 (0.60) | ALDH1A1MAPTLMNARAB9ANPSR1 | |
| Dinitrophenylene SCHEMBL27728956 | 0.77 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNAGAARAB9A | |
| Quinoline SCHEMBL27814435 | 0.75 | POLB (0.64) | ALDH1A1MAPTLMNARAB9ANPC1 | |
| Quinoline SCHEMBL5874220 | 0.74 | ALDH1A1 (0.68) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL366012 | 0.73 | ALDH1A1 (0.62) | ALDH1A1MAPTLMNAGAARAB9A | |
| SCHEMBL30626616 | 0.73 | BAZ1A (0.60) | ALDH1A1MAPTLMNAGAARAB9A | |
| SCHEMBL1012937 | 0.73 | BAZ1A (0.60) | ALDH1A1MAPTLMNAGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10620143-B2 | Sensor and method of detecting an analyte using 19F NMR | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-04-14 | — | — | US | disclosed |
| WO-2016011194-A1 | SENSOR AND METHOD OF DETECTING AN ANALYTE USING 19F NMR | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-21 | — | — | WO | disclosed |
| US-20160018344-A1 | SENSOR AND METHOD OF DETECTING AN ANALYTE USING 19F NMR | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2016-01-21 | — | — | US | disclosed |