Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 15/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1338576 | 0.88 | S1PR1 (0.40) | S1PR1NPC1ALDH1A1MAPTNFKB1 | |
| SCHEMBL1336492 | 0.85 | S1PR1 (0.41) | S1PR1NPC1ALDH1A1MAPTNFKB1 | |
| SCHEMBL1337475 | 0.84 | S1PR1 (0.46) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL1744005 | 0.83 | S1PR1 (0.39) | S1PR1NPC1ALDH1A1MAPTNFKB1 | |
| SCHEMBL1337394 | 0.83 | S1PR1 (0.42) | S1PR1NPC1ALDH1A1MAPTNFKB1 | |
| SCHEMBL1337453 | 0.80 | NPC1 (0.39) | S1PR1NPC1ALDH1A1MAPTNFKB1 | |
| SCHEMBL1743920 | 0.78 | S1PR1 (0.37) | S1PR1S1PR5S1PR3 | |
| SCHEMBL1337688 | 0.76 | S1PR1 (0.41) | S1PR1S1PR5S1PR3 | |
| SCHEMBL12129820 | 0.75 | ALDH1A1 (0.42) | S1PR1NPC1ALDH1A1MAPTNFKB1 | |
| SCHEMBL1338057 | 0.73 | S1PR1 (0.46) | S1PR1ALDH1A1S1PR5S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2387571-A1 | OXADIAZOLE DERIVATIVES AS SLPL RECEPTOR AGONISTS | Almirall S.A. (ES) | 2011-11-23 | — | — | EP | disclosed |
| US-8041930-B2 | Data processing apparatus and method for controlling thread access of register sets when selectively operating in secure and non-secure domains | ARM LIMITED (GB) | 2011-10-18 | — | — | US | disclosed |
| WO-2010081692-A1 | OXADIAZOLE DERIVATIVES AS SLPL RECEPTOR AGONISTS | ALMIRALL, S.A. (ES) | 2010-07-22 | — | — | WO | disclosed |