Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 11/20 | 0.49 |
| ▸ | RARG | P13631 | 11/20 | 0.49 |
| ▸ | RARA | P10276 | 9/20 | 0.49 |
| ▸ | ERN1 | O75460 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL16147145 | 0.97 | MEN1 (0.51) | MEN1KMT2ATHRBRECQLNR2E1 | |
| Methane SCHEMBL16147650 | 0.84 | RARB (0.56) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL1250065 | 0.75 | ACMSD (0.57) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL14157072 | 0.72 | MIF (0.57) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL5047765 | 0.72 | RARB (0.60) | MEN1KMT2ARARBRARGRARA | |
| Methane SCHEMBL16146729 | 0.72 | RARB (0.60) | MEN1KMT2ARARBRARGRARA | |
| SCHEMBL3020401 | 0.71 | ESR1 (0.67) | MEN1KMT2ARARBRARGRARA | |
| SCHEMBL20979999 | 0.70 | MEN1 (0.57) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL30526912 | 0.70 | RARB (0.62) | MEN1KMT2ARARBRARGRARA | |
| SCHEMBL29049592 | 0.70 | RARB (0.62) | MEN1KMT2ARARBRARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3638209-A1 | NANOPARTICLE COMPOSITIONS, METHODS OF FABRICATION, AND USE FOR DRUG DELIVERY | Dignity Health (US) | 2020-04-22 | — | — | EP | disclosed |
| WO-2018232366-A1 | NANOPARTICLE COMPOSITIONS, METHODS OF FABRICATION, AND USE FOR DRUG DELIVERY | DIGNITY HEALTH (US) | 2018-12-20 | — | — | WO | disclosed |
| EP-3393481-A1 | OIL-IN-WATER EMULSIONS INCLUDING RETINOIC ACID | NOVARTIS AG (CH) | 2018-10-31 | — | — | EP | disclosed |
| WO-2017192606-A1 | METHODS OF PRODUCING SPECIALIZED CARDIO-LIKE CELLS FROM STEM CELL | EMORY UNIVERSITY (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017108902-A1 | OIL-IN-WATER EMULSIONS INCLUDING RETINOIC ACID | NOVARTIS AG (CH) | 2017-06-29 | — | — | WO | disclosed |
| EP-2613776-A2 | COMPOSITION AND METHOD FOR MUSCLE REPAIR AND REGENERATION | Thomas Jefferson University (US) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012030919-A2 | COMPOSITION AND METHOD FOR MUSCLE REPAIR AND REGENERATION | THOMAS JEFFERSON UNIVERSITY (US) | 2012-03-08 | — | — | WO | disclosed |