Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.57 |
| ▸ | RARB | P10826 | 13/20 | 0.46 |
| ▸ | RARG | P13631 | 13/20 | 0.46 |
| ▸ | RARA | P10276 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21482157 | 0.88 | RARB (0.55) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL17169672 | 0.73 | MEN1 (0.61) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL29359220 | 0.72 | MEN1 (1.00) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL173380 | 0.72 | MEN1 (1.00) | MEN1KMT2ATHRBRECQLNR2E1 | |
| Methane SCHEMBL16147145 | 0.70 | MEN1 (0.51) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL174449 | 0.70 | MEN1 (0.51) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL14157072 | 0.70 | MIF (0.57) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL1250065 | 0.70 | ACMSD (0.57) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL3020401 | 0.69 | ESR1 (0.67) | MEN1KMT2ARARBRARGRARA | |
| SCHEMBL19235986 | 0.68 | MEN1 (0.70) | MEN1KMT2ATHRBRECQLNR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230255937-A1 | THERAPEUTIC AGENT FOR KERATOCONJUNCTIVE DISORDERS | YAMAGUCHI UNIVERSITY (JP) | 2023-08-17 | — | — | US | disclosed |
| US-10537556-B2 | Therapeutic agent for keratoconjunctive disorders | YAMAGUCHI UNIVERSITY (JP) | 2020-01-21 | — | — | US | disclosed |
| US-20190134002-A1 | THERAPEUTIC AGENT FOR KERATOCONJUNCTIVE DISORDERS | YAMAGUCHI UNIVERSITY (JP) | 2019-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10537556-B2 | Therapeutic agent for keratoconjunctive disorders | RARG, RARB, RARA | MEN1 4882/4885KMT2A 3104/4885THRB 382/4885 |
| US-20230255937-A1 | THERAPEUTIC AGENT FOR KERATOCONJUNCTIVE DISORDERS | RARG, RARB, RARA | MEN1 4882/4885KMT2A 3104/4885THRB 382/4885 |
| US-20190134002-A1 | THERAPEUTIC AGENT FOR KERATOCONJUNCTIVE DISORDERS | RARG, RARB, RARA | MEN1 4882/4885KMT2A 3104/4885THRB 382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.