Sugi Predict

Sugi Predict / Compounds / SCHEMBL17445347

SCHEMBL17445347

SCHEMBL17445347

c1ccc(-n2c3ccccc3c3c4c(c5ccccc5c32)c2ccccc2c2c4c3ccccc3n2-c2ccc(-c3ccc(-n4c5ccccc5c5ccccc54)cc3)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.58
▸ KDM4E B2RXH2 1/20 0.58
▸ ATM Q13315 1/20 0.58
▸ HDAC4 P56524 1/20 0.43
▸ KMT2A Q03164 3/20 0.38
▸ IL1R1 P14778 1/20 0.38
▸ MEN1 O00255 2/20 0.37
▸ ALDH1A1 P00352 2/20 0.37
▸ MAPT P10636 1/20 0.37
▸ HTT P42858 1/20 0.37
▸ PTPN1 P18031 2/20 0.35
▸ MAPK8 P45983 2/20 0.35
▸ MAPK1 P28482 1/20 0.34
▸ PGR P06401 1/20 0.34
▸ MAPK9 P45984 1/20 0.34
▸ HSD17B10 Q99714 2/20 0.33
▸ POLB P06746 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ BRCA1 P38398 1/20 0.33
▸ FOLH1 Q04609 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17445349 0.95 L3MBTL1 (0.50) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL17445392 0.93 L3MBTL1 (0.50) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL17451662 0.92 L3MBTL1 (0.53) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL18435884 0.92 L3MBTL1 (0.53) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL19046739 0.90 L3MBTL1 (0.44) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL20311935 0.90 L3MBTL1 (0.47) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL17123101 0.90 L3MBTL1 (0.50) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL17123107 0.89 L3MBTL1 (0.53) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL10027635 0.89 L3MBTL1 (0.56) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL10205974 0.89 L3MBTL1 (0.56) L3MBTL1KDM4EATMHDAC4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9780314-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2017-10-03 — — US disclosed
US-9780314-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2017-10-03 — — US disclosed
US-20160020408-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2016-01-21 — — US disclosed
US-20160020408-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2016-01-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160020408-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF OR51E2, NFE2L2, ORAI2 L3MBTL1 942/4885KDM4E 446/4885ATM 2208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.