Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 9/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 9/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 9/20 | 0.32 |
| ▸ | PRKAB2 | O43741 | 8/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 8/20 | 0.32 |
| ▸ | PRKAG3 | Q9UGI9 | 8/20 | 0.32 |
| ▸ | PRKAG2 | Q9UGJ0 | 8/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17445740 | 1.00 | MAPT (0.51) | MAPTTHRBLMNABCHEALDH1A1 | |
| SCHEMBL17445730 | 1.00 | MAPT (0.51) | MAPTTHRBLMNABCHEALDH1A1 | |
| SCHEMBL15373594 | 1.00 | MAPT (0.51) | MAPTTHRBLMNABCHEALDH1A1 | |
| SCHEMBL7153071 | 0.88 | ALDH1A1 (0.41) | MAPTBCHEALDH1A1 | |
| SCHEMBL907186 | 0.88 | ALDH1A1 (0.41) | MAPTBCHEALDH1A1 | |
| SCHEMBL13689312 | 0.88 | ALDH1A1 (0.41) | MAPTBCHEALDH1A1 | |
| SCHEMBL7151311 | 0.88 | ALDH1A1 (0.41) | MAPTBCHEALDH1A1 | |
| SCHEMBL907185 | 0.88 | ALDH1A1 (0.41) | MAPTBCHEALDH1A1 | |
| SCHEMBL1014606 | 0.85 | MAPT (0.51) | MAPTTHRBLMNABCHEALDH1A1 | |
| SCHEMBL1014604 | 0.85 | MAPT (0.51) | MAPTTHRBLMNABCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160016969-A1 | ISOHEXIDE MONOTRIFLATES AND PROCESS FOR SYNTHESIS THEREOF | ARCHER DANIELS MIDLAND COMPANY (US) | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016969-A1 | ISOHEXIDE MONOTRIFLATES AND PROCESS FOR SYNTHESIS THEREOF | PPIP5K2, TALDO1, MSH2 | MAPT 2573/4885THRB 3354/4885LMNA 1370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.