Sugi Predict

Sugi Predict / Compounds / SCHEMBL1744586

SCHEMBL1744586

SCHEMBL1744586

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]2O[C@@H](n3cnc4c(N)ncnc43)[C@H](O)[C@@H]2O)[C@@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ P2RY1 P47900 7/20 1.00
▸ P2RY2 P41231 3/20 1.00
▸ P2RX1 P51575 3/20 1.00
▸ P2RX3 P56373 3/20 1.00
▸ ALDH1A1 P00352 2/20 1.00
▸ SRC P12931 2/20 1.00
▸ SMN1; SMN2 Q16637 2/20 1.00
▸ P2RX2 Q9UBL9 2/20 1.00
▸ P2RX4 Q99571 1/20 1.00
▸ TRPM2 O94759 2/20 0.93
▸ MACROD2 A1Z1Q3 1/20 0.93
▸ SIRT6 Q8N6T7 1/20 0.93
▸ MACROD1 Q9BQ69 1/20 0.93
▸ TAS1R3 Q7RTX0 2/20 0.85
▸ TAS1R1 Q7RTX1 2/20 0.85
▸ DNPH1 O43598 1/20 0.85
▸ PRKAB2 O43741 1/20 0.85
▸ LDHA P00338 1/20 0.85
▸ ADRB2 P07550 1/20 0.85
▸ FBP1 P09467 1/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diadenosine Tetraphosphate SCHEMBL849869 1.00 P2RY1 (1.00) P2RY1P2RY2P2RX1P2RX3ALDH1A1
SCHEMBL6516963 1.00 P2RY1 (1.00) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Diadenosine Tetraphosphate SCHEMBL10069136 1.00 P2RY1 (1.00) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Diadenosine Tetraphosphate SCHEMBL4363130 1.00 P2RY1 (1.00) P2RY1P2RY2P2RX1P2RX3ALDH1A1
SCHEMBL4357990 1.00 P2RY1 (1.00) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Diadenosine Tetraphosphate SCHEMBL14205963 1.00 P2RY1 (1.00) P2RY1P2RY2P2RX1P2RX3ALDH1A1
SCHEMBL2934890 1.00 P2RY1 (1.00) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Diadenosine Tetraphosphate SCHEMBL4069414 1.00 P2RY1 (1.00) P2RY1P2RY2P2RX1P2RX3ALDH1A1
SCHEMBL21067711 1.00 P2RY1 (1.00) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Diadenosine Tetraphosphate SCHEMBL31079560 1.00 P2RY1 (1.00) P2RY1P2RY2P2RX1P2RX3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 265 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119842165-A Method for preparing exterior wall flame-retardant material from waste plastics 东莞市众一新材料科技有限公司 2025-04-18 — — CN claimed
US-20230321209-A1 MODIFIED MYCOBACTERIUM BOVIS VACCINES VALO THERAPEUTICS OY (FI) 2023-10-12 — — US claimed
US-20230293580-A1 SARS-COV2-SPECIFIC T CELL COMPOSITIONS AND THEIR USE IN TREATING AND PREVENTING CORONAVIRUS AND OTHER RESPIRATORY VIRUS INFECTIONS BAYLOR COLLEGE OF MEDICINE 2023-09-21 — — US claimed
EP-4240339-A1 COMPOSITIONS AND METHODS TO PROMOTE THYMIC FUNCTION Fred Hutchinson Cancer Center (US) 2023-09-13 — — EP claimed
US-20230263800-A1 COMPOSITIONS AND METHODS TO PROMOTE THYMIC FUNCTION FRED HUTCHINSON CANCER CENTER (US) 2023-08-24 — — US claimed
EP-4208191-A1 MODIFIED MYCOBACTERIUM BOVIS VACCINES Valo Therapeutics Oy (FI) 2023-07-12 — — EP claimed
WO-2023094993-A1 IMPROVED VIRUS-SPECIFIC T CELL BAYLOR COLLEGE OF MEDICINE (US) 2023-06-01 — — WO claimed
CN-116157149-A Modified mycobacterium bovis vaccine 瓦洛治疗公司 2023-05-23 — — CN claimed
EP-4121514-A1 SARS-COV2-SPECIFIC T CELL COMPOSITIONS AND THEIR USE IN TREATING AND PREVENTING CORONAVIRUS AND OTHER RESPIRATORY VIRUS INFECTIONS Baylor College of Medicine (US) 2023-01-25 — — EP claimed
US-20220331377-A1 DELIVERY VEHICLE FOR IN SITU DELIVERING OF PHARMACEUTICAL AGENTS RIVER STONE BIOTECH ISG APS (DK) 2022-10-20 — — US claimed
EP-4003378-A1 ANTIGEN-SPECIFIC T CELL BANKS AND METHODS OF MAKING AND USING THE SAME THERAPEUTICALLY Baylor College of Medicine (US) 2022-06-01 — — EP claimed
US-20220152163-A1 Compositions and Methods for Treating Pathological Calcification and Ossification UNIV YALE (US) 2022-05-19 — — US claimed
WO-2022098776-A1 COMPOSITIONS AND METHODS TO PROMOTE THYMIC FUNCTION FRED HUTCHINSON CANCER RESEARCH CENTER (US) 2022-05-12 — — WO claimed
WO-2022049002-A1 PEPTIVAX THERAPY VALO THERAPEUTICS OY (FI) 2022-03-10 — — WO claimed
WO-2022049001-A1 MODIFIED MYCOBACTERIUM BOVIS VACCINES THE UNIVERSITY OF HELSINKI (FI) 2022-03-10 — — WO claimed
WO-2017114796-A1 ADENOSYLHOMOCYSTEINASE BINDING SUBSTANCES FOR MEDICAL USE LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) 2017-07-06 — — WO claimed
US-8608922-B2 Biosensor for continuous monitoring of metabolites and proteins and methods of manufacture thereof THE UNIVERSITY OF CONNECTICUT (US) 2013-12-17 — — US claimed
US-20100116691-A1 BIOSENSOR FOR CONTINUOUS MONITORING OF METABOLITES AND PROTEINS AND METHODS OF MANUFACTURE THEREOF UNIVERSITY OF CONNECTICUT (US) 2010-05-13 — — US claimed
EP-0969848-A1 USE OF DIADENOSINE POLYPHOSPHATES FOR REDUCING BLOOD PRESSURE Clemson University (US) 2000-01-12 — — EP claimed
WO-1998030222-A1 USE OF DIADENOSINE POLYPHOSPHATES FOR REDUCING BLOOD PRESSURE CLEMSON UNIVERSITY (US) 1998-07-16 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230263800-A1 COMPOSITIONS AND METHODS TO PROMOTE THYMIC FUNCTION BMP4, P2RY2, GPR39 P2RY1 6/4885P2RY2 2/4885P2RX1 17/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.