SCHEMBL174463

SCHEMBL174463

O=CCCCCCCCCCCCCCCCCC(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.63
TSHR P16473 2/20 0.63
NFKB1 P19838 1/20 0.63
PMP22 Q01453 1/20 0.63
MAPT P10636 3/20 0.62
ABCC4 O15439 1/20 0.62
PPARG P37231 4/20 0.56
PPARD Q03181 4/20 0.56
PPARA Q07869 4/20 0.56
TERT O14746 3/20 0.56
PTPN1 P18031 3/20 0.56
BLM P54132 2/20 0.56
HSD17B10 Q99714 2/20 0.56
FABP4 P15090 2/20 0.56
F7 P08709 2/20 0.56
F3 P13726 2/20 0.56
GMNN O75496 1/20 0.56
USP2 O75604 1/20 0.56
CYP1A2 P05177 1/20 0.56
POLB P06746 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL380888 1.00 LMNA (0.63) LMNATSHRNFKB1PMP22MAPT
SCHEMBL258956 1.00 LMNA (0.63) LMNATSHRNFKB1PMP22MAPT
SCHEMBL14798059 1.00 LMNA (0.63) LMNATSHRNFKB1PMP22MAPT
SCHEMBL274867 1.00 LMNA (0.63) LMNATSHRNFKB1PMP22MAPT
SCHEMBL15526298 1.00 LMNA (0.63) LMNATSHRNFKB1PMP22MAPT
SCHEMBL648618 1.00 LMNA (0.63) LMNATSHRNFKB1PMP22MAPT
SCHEMBL2014792 1.00 LMNA (0.63) LMNATSHRNFKB1PMP22MAPT
SCHEMBL1603841 1.00 LMNA (0.63) LMNATSHRNFKB1PMP22MAPT
SCHEMBL1654500 1.00 LMNA (0.63) LMNATSHRNFKB1PMP22MAPT
SCHEMBL17744969 1.00 LMNA (0.63) LMNATSHRNFKB1PMP22MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 903 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118829251-A Solar cell, preparation method thereof, photovoltaic module, system and power utilization device 宁德时代新能源科技股份有限公司 2024-10-22 CN claimed
WO-2024149820-A1 NMU RECEPTOR 2 AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2024-07-18 WO claimed
CN-118255864-A GIP receptor agonists and uses thereof 杭州中美华东制药有限公司 2024-06-28 CN claimed
CN-118252921-A Use of GIP receptor agonists 杭州中美华东制药有限公司 2024-06-28 CN claimed
WO-2024133382-A1 GLP1/GIP/NPY2 RECEPTOR TRIPLE AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2024-06-27 WO claimed
CN-118079021-A Treatment or amelioration of metabolic disorders using GLP-1 receptor agonists coupled to Gastric Inhibitory Peptide Receptor (GIPR) antagonists 美国安进公司 2024-05-28 CN claimed
US-11965039-B2 Compstatin analogues and their medical uses ZP SPV 3 K/S (DK) 2024-04-23 US claimed
EP-4351630-A1 TREATMENT OF OBESITY AND OBESITY-RELATED DISORDERS Antag Therapeutics ApS (DK) 2024-04-17 EP claimed
EP-3551651-B1 ACYLATED GLP-1/GLP-2 DUAL AGONISTS ZEALAND PHARMA AS (DK) 2024-03-06 EP claimed
CN-117384274-A Acylated GLP-1/GLP-2 dual agonists 西兰制药公司 2024-01-12 CN claimed
EP-3046573-A2 AMYLIN ANALOGUES Zealand Pharma A/S (DK) 2016-07-27 EP claimed
WO-2015067716-A1 GLUCAGON-GLP-1-GIP TRIPLE AGONIST COMPOUNDS ZEALAND PHARMA A/S (DK) 2015-05-14 WO claimed
WO-2015040182-A2 AMYLIN ANALOGUES ZEALAND PHARMA A/S (DK) 2015-03-26 WO claimed
CN-103906528-A Methods of treating diabetes with sustained release formulations of GLP-1 receptor agonists AMYLIN PHARMACEUTICALS INC 2014-07-02 CN claimed
US-7541430-B2 Peptides for use in treating obesity NOVO NORDISK A/S (DK) 2009-06-02 US claimed
US-20070244054-A1 Peptides for use in treating obesity NOVO NORDISK A/S (DK) 2007-10-18 US claimed
EP-1625158-A2 PEPTIDES FOR USE IN TREATING OBESITY NOVO NORDISK A/S (DK) 2006-02-15 EP claimed
WO-2004099246-A2 PEPTIDES FOR USE IN TREATING OBESITY NOVO NORDISK A/S (DK) 2004-11-18 WO claimed
US-4440781-A TRANQUILIZERS; ANTICONVULSANTS; ANTIDEPRESSANTS; ALCOHOL AND TOBACCO WITHDRAWAL THE VINOXEN COMPANY, INC. (US) 1984-04-03 US claimed
US-4097665-A Diacylnucleosides and process for preparing the same ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1978-06-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11965039-B2 Compstatin analogues and their medical uses C1QBP, C9, VIP LMNA 1380/4885TSHR 1041/4885NFKB1 2017/4885
US-20070244054-A1 Peptides for use in treating obesity NPY4R, GLP1R, NPY1R LMNA 3088/4885TSHR 296/4885NFKB1 2722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.