Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL216719 | 0.88 | HPRT1 (0.50) | HPRT1ALDH1A1HSD17B10CYP1A2HPGD | |
| SCHEMBL26149 | 0.79 | PTPN1 (0.41) | HPRT1ALDH1A1HSD17B10CYP1A2HPGD | |
| Chrysene SCHEMBL11099806 | 0.75 | HPRT1 (0.61) | HPRT1ALDH1A1HSD17B10CYP1A2HPGD | |
| Phenanthrene SCHEMBL23068724 | 0.73 | ALDH1A1 (0.50) | HPRT1ALDH1A1HSD17B10CYP1A2HPGD | |
| Chrysene SCHEMBL16034318 | 0.73 | ALDH1A1 (0.68) | HPRT1ALDH1A1HSD17B10CYP1A2HPGD | |
| SCHEMBL29769915 | 0.72 | HPRT1 (0.78) | HPRT1ALDH1A1HSD17B10CYP1A2HPGD | |
| SCHEMBL593261 | 0.72 | HPRT1 (0.78) | HPRT1ALDH1A1HSD17B10CYP1A2HPGD | |
| Chrysene SCHEMBL3747550 | 0.72 | HPRT1 (0.78) | HPRT1ALDH1A1HSD17B10CYP1A2HPGD | |
| SCHEMBL29445992 | 0.72 | HPRT1 (0.78) | HPRT1ALDH1A1HSD17B10CYP1A2HPGD | |
| Phenanthrene SCHEMBL28600323 | 0.70 | ALDH1A1 (0.57) | HPRT1ALDH1A1HSD17B10CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385980-B1 | BACTERIAL VACCINES WITH CELL WALL-ASSOCIATED CERAMIDE-LIKE GLYCOLIPIDS AND USES THEREOF | ALBERT EINSTEIN COLLEGE MEDICINE INC (US) | 2018-04-18 | — | — | EP | disclosed |
| WO-2014072809-A2 | BENZOMORPHAN ANALOGS AND THE USE THEREOF | PURDUE PHARMA L.P. (US) | 2014-05-15 | — | — | WO | disclosed |
| EP-2385980-A1 | BACTERIAL VACCINES WITH CELL WALL-ASSOCIATED CERAMIDE-LIKE GLYCOLIPIDS AND USES THEREOF | The Albert Einstein College Of Medicine Of Yeshiva University (US) | 2011-11-16 | — | — | EP | disclosed |
| US-8040452-B2 | Manufacturing method for a thin film transistor-liquid crystal display having an insulating layer exposing portions of a gate island | BEIJING BOE OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) | 2011-10-18 | — | — | US | disclosed |
| WO-2010081026-A1 | BACTERIAL VACCINES WITH CELL WALL-ASSOCIATED CERAMIDE-LIKE GLYCOLIPIDS AND USES THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY, A DIVISION OF YESHIVA UNIVERSITY (US) | 2010-07-15 | — | — | WO | disclosed |