SCHEMBL26149

SCHEMBL26149

[CH]1C(c2cccc3ccccc23)=Cc2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.41
POLB P06746 1/20 0.39
ALDH1A1 P00352 5/20 0.37
TSHR P16473 4/20 0.37
HSD17B10 Q99714 4/20 0.37
CYP2A6 P11509 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
KDM4E B2RXH2 2/20 0.37
ALPL P05186 1/20 0.37
GAA P10253 1/20 0.37
NISCH Q9Y2I1 1/20 0.36
ENPP3 O14638 1/20 0.36
ENPP1 P22413 1/20 0.36
HPGD P15428 3/20 0.35
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 1/20 0.35
KEAP1 Q14145 1/20 0.35
MAPK1 P28482 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL216719 0.91 HPRT1 (0.50) PTPN1POLBALDH1A1TSHRHSD17B10
SCHEMBL5379562 0.83 ALDH1A1 (0.36) ALDH1A1TSHRHSD17B10KDM4EGAA
SCHEMBL1744646 0.79 HPRT1 (0.45) POLBALDH1A1TSHRHSD17B10CYP2A6
SCHEMBL5599457 0.77 CYP1A2 (0.47) ALDH1A1HSD17B10CYP2A6TDP1KDM4E
SCHEMBL8617499 0.75 MEN1 (0.45) ALDH1A1CYP2A6KDM4EHPGDCYP1A2
SCHEMBL5600175 0.73 METAP2 (0.35) ALDH1A1KDM4EHPGDMAPT
SCHEMBL8615594 0.73 KDM4E (0.33) ALDH1A1KDM4EENPP3ENPP1HPGD
SCHEMBL25302086 0.72 ALDH1A1 (0.59) PTPN1POLBALDH1A1TSHRHSD17B10
SCHEMBL7943843 0.72 LMNA (0.30) TSHR
SCHEMBL29350007 0.72 ALDH1A1 (0.59) PTPN1POLBALDH1A1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 399 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106103507-B Process for the preparation of ethylene propylene copolymers 埃克森美孚化学专利公司 2019-04-05 CN claimed
US-20140219911-A1 DIHYDROXYBIPYRIDINE COMPLEXES OF RUTHENIUM AND IRIDIUM FOR WATER OXIDATION AND HYDROGENATION THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2014-08-07 US claimed
WO-2013033018-A2 DIHYDROXYBIPYRIDINE COMPLEXES OF RUTHENIUM AND IRIDIUM FOR WATER OXIDATION AND HYDROGENATION DREXEL UNIVERSITY (US) 2013-03-07 WO claimed
EP-0993478-B2 OLEFIN POLYMERIZATION PROCESS BOREALIS TECH OY (FI) 2011-01-19 EP claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
EP-1195386-B1 TRANSITION METAL CATALYST COMPONENT FOR POLYMERIZATION AND PROCESS FOR PRODUCING POLYMER WITH THE SAME DENKI KAGAKU KOGYO KK (JP) 2007-06-20 EP claimed
US-6921799-B1 Olefin polymerization process BOREALIS A/S (DK) 2005-07-26 US claimed
US-6891004-B2 Transition metal catalyst component for polymerization, and method for producing a polymer by means thereof DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2005-05-10 US claimed
CN-1157427-C Polymerization method for olefrines �����ɷ� 2004-07-14 CN claimed
CN-1154668-C Dicyclopentradiene diene compound 2004-06-23 CN claimed
EP-0872492-B1 Transition metal compound as catalyst component for polymerization, aromatic vinyl compound-olefin copolymer having stereoregularity and method for its preparation by means of the transition metal compound as catalyst component DENKI KAGAKU KOGYO KK (JP) 2003-12-03 EP claimed
US-20030149201-A1 Transition metal catalyst component for polymerization, and method for producing a polymer by means thereof DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2003-08-07 US claimed
US-20030096926-A1 Transition metal catalyst component for polymerization and process for producing polymer with the same DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2003-05-22 US claimed
EP-1195386-A1 TRANSITION METAL CATALYST COMPONENT FOR POLYMERIZATION AND PROCESS FOR PRODUCING POLYMER WITH THE SAME DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2002-04-10 EP claimed
US-20010051699-A1 Transition metal catalyst component for polymerization, aromatic vinyl compound polymer having stereoregularity and method for its preparation by means of the catalyst component DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2001-12-13 US claimed
US-6235855-B1 METALLOCENE CONTAINING AN UNSUBSTITUTED OR SUBSTITUTED BENZINDENYL GROUP DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2001-05-22 US claimed
CN-1263894-A Dicyclopentradiene diene compound DOW CHEMICAL CO (US) 2000-08-23 CN claimed
CN-1260807-A Polymerization method for olefrines BOREALL AS (DK) 2000-07-19 CN claimed
EP-0872492-A2 Transition metal compound as catalyst component for polymerization, aromatic vinyl compound-olefin copolymer having stereoregularity and method for its preparation by means of the transition metal compound as catalyst component DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1998-10-21 EP claimed
CN-1156997-A Dicyclopentadienyl diene complexes DOW CHEMICAL CO (US) 1997-08-13 CN claimed