SCHEMBL1744694

SCHEMBL1744694

C[C@@H](CC(=O)O)c1ccc(OC2CCc3ccccc32)cc1

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1744683 1.00 FFAR1 (0.72) FFAR1
SCHEMBL10441354 0.84 FFAR1 (1.00) FFAR1
SCHEMBL11998990 0.84 FFAR1 (0.60) FFAR1
SCHEMBL14567353 0.83 FFAR1 (1.00) FFAR1
SCHEMBL3854202 0.83 FFAR1 (1.00) FFAR1
SCHEMBL14567262 0.82 FFAR1 (0.59) FFAR1
SCHEMBL1745136 0.79 FFAR1 (0.57) FFAR1
SCHEMBL1746615 0.79 FFAR1 (0.60) FFAR1
SCHEMBL1746407 0.79 FFAR1 (0.60) FFAR1
SCHEMBL1508616 0.78 FFAR1 (1.00) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2385032-A1 GPR40 Receptor function regulator Takeda Pharmaceutical Company Limited (JP) 2011-11-09 EP disclosed
US-7960369-B2 Receptor function regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-06-14 US disclosed