Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GFRA2 | O00451 | 1/20 | 0.42 |
| ▸ | GFRA3 | O60609 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1744683 | 0.79 | FFAR1 (0.72) | FFAR1 | |
| SCHEMBL1744694 | 0.79 | FFAR1 (0.72) | FFAR1 | |
| SCHEMBL12017975 | 0.79 | IDO1 (0.61) | FFAR1IDO1GFRA2GFRA3 | |
| SCHEMBL1745291 | 0.77 | MAPK1 (0.63) | FFAR1CYP1A2CYP2C9CYP2C19IDO1 | |
| SCHEMBL1746615 | 0.76 | FFAR1 (0.60) | FFAR1GAAIDO1GFRA2GFRA3 | |
| SCHEMBL1746407 | 0.76 | FFAR1 (0.60) | FFAR1IDO1 | |
| SCHEMBL8529487 | 0.76 | IDO1 (0.54) | FFAR1IDO1GFRA2GFRA3 | |
| SCHEMBL21142124 | 0.76 | IDO1 (0.54) | FFAR1IDO1GFRA2GFRA3 | |
| SCHEMBL1633343 | 0.74 | FFAR1 (0.57) | FFAR1 | |
| SCHEMBL1745432 | 0.74 | FFAR1 (0.57) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385032-A1 | GPR40 Receptor function regulator | Takeda Pharmaceutical Company Limited (JP) | 2011-11-09 | — | — | EP | disclosed |
| US-7960369-B2 | Receptor function regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-06-14 | — | — | US | disclosed |