Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 8/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.31 |
| ▸ | MLNR | O43193 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15384735 | 0.97 | PDK2 (0.39) | PDK2MCL1SLC6A9GRIA1CACNG8 | |
| SCHEMBL17447205 | 0.97 | PDK2 (0.40) | PDK2MCL1ESR2GRIA1CACNG8 | |
| SCHEMBL17808008 | 0.94 | PDK2 (0.38) | PDK2MCL1ESR2 | |
| SCHEMBL19531981 | 0.94 | ESR2 (0.39) | PDK2MCL1ESR2MLNRNR1I2 | |
| SCHEMBL15866067 | 0.93 | PDK2 (0.39) | PDK2ESR2MLNRNR1I2CHRM2 | |
| SCHEMBL15866065 | 0.93 | PDK2 (0.39) | PDK2ESR2MLNRNR1I2CHRM2 | |
| SCHEMBL15791645 | 0.93 | PDK2 (0.36) | PDK2MCL1SLC6A9S1PR1 | |
| SCHEMBL20726889 | 0.93 | PDK2 (0.37) | PDK2MCL1SLC6A9NPC1RAB9A | |
| SCHEMBL12758709 | 0.92 | PDK2 (0.38) | PDK2ESR2MLNRNR1I2CHRM2 | |
| SCHEMBL15576857 | 0.92 | PDK2 (0.38) | PDK2ESR2MLNRNR1I2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160020403-A1 | ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE | IDEMITSU KOSAN CO., LTD. (JP) | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160020403-A1 | ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE | SLC18A1, SLC18A2, AOC2 | PDK2 833/4885MCL1 4180/4885SLC6A9 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.