Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9664850 | 0.87 | KCNA5 (0.52) | NPC1RAB9AALDH1A1HTTTSHR | |
| SCHEMBL6331300 | 0.85 | NPC1 (0.62) | NPC1RAB9AALDH1A1HTTTSHR | |
| SCHEMBL26147436 | 0.83 | NPC1 (0.60) | NPC1RAB9AALDH1A1HTTMAPT | |
| SCHEMBL17442696 | 0.83 | HIF1A (0.57) | NPC1RAB9A | |
| SCHEMBL1433979 | 0.81 | NPC1 (0.72) | NPC1RAB9AALDH1A1HTTKMT2A | |
| SCHEMBL5769261 | 0.81 | NPC1 (0.71) | NPC1RAB9AALDH1A1HTTKMT2A | |
| SCHEMBL754896 | 0.81 | TSHR (0.55) | NPC1RAB9AALDH1A1HTTMAPT | |
| SCHEMBL30858769 | 0.81 | NPC1 (1.00) | NPC1RAB9AALDH1A1HTTKMT2A | |
| SCHEMBL2749188 | 0.80 | ALDH1A1 (0.66) | NPC1RAB9AALDH1A1HTTMAPT | |
| SCHEMBL31504505 | 0.80 | TAAR1 (0.49) | NPC1RAB9AHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017001924-A1 | THERAPEUTIC INHIBITORY COMPOUDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2017-01-05 | — | — | WO | disclosed |
| WO-2016011209-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2016-01-21 | — | — | WO | disclosed |