Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30101811 | 0.87 | KDM4A (0.43) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL15659479 | 0.84 | TSHR (0.44) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3328937 | 0.83 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL17447296 | 0.81 | NPC1 (0.68) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1759206 | 0.81 | TSHR (0.55) | TSHRSMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL4624413 | 0.81 | TSHR (0.55) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL753192 | 0.80 | TSHR (0.51) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29220293 | 0.80 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL4623289 | 0.79 | TSHR (0.54) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4623701 | 0.79 | TSHR (0.62) | TSHRNPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430921-A2 | Substituted benzene fungicides | E.I. Du Pont De Nemours And Company (US) | 2012-03-21 | — | — | EP | disclosed |
| CN-101686688-A | substituted benzene fungicides | DU PONT | 2010-03-31 | — | — | CN | disclosed |