Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 6/20 | 0.34 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1744046 | 0.97 | LMNA (0.53) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL2763330 | 0.92 | LMNA (0.49) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL20034199 | 0.85 | LMNA (0.50) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL19645483 | 0.83 | LMNA (0.45) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL13086968 | 0.80 | LMNA (0.54) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8378687 | 0.80 | LMNA (0.56) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL2784245 | 0.80 | LMNA (0.56) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL12657374 | 0.80 | LMNA (0.56) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL3426791 | 0.77 | LMNA (0.59) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL11292903 | 0.77 | LMNA (0.59) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385845-A1 | CONTRAST MEDIA COMPOSITIONS | GE HEALTHCARE AS (NO) | 2011-11-16 | — | — | EP | disclosed |
| US-D647037-S1 | Tire tread | LO TSAI JEN | 2011-10-18 | — | — | US | disclosed |
| WO-2010079201-A1 | CONTRAST MEDIA COMPOSITIONS | GE HEALTHCARE AS (NO) | 2010-07-15 | — | — | WO | disclosed |