Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 7/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL1744741 | 0.97 | LMNA (0.51) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL2763330 | 0.95 | LMNA (0.49) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL20034199 | 0.87 | LMNA (0.50) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL19645483 | 0.85 | LMNA (0.45) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8378687 | 0.82 | LMNA (0.56) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL2784245 | 0.82 | LMNA (0.56) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL12657374 | 0.82 | LMNA (0.56) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL3426791 | 0.80 | LMNA (0.59) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL11292903 | 0.80 | LMNA (0.59) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL619944 | 0.79 | LMNA (0.60) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2917174-B1 | PREPARATION OF INTERMEDIATES OF X-RAY CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2018-09-12 | — | — | EP | claimed |
| US-9403757-B2 | Preparation of intermediates of X-ray contrast agents | GE HEALTHCARE AS (NO) | 2016-08-02 | — | — | US | claimed |
| US-20150274645-A1 | PREPARATION OF INTERMEDIATES OF X-RAY CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2015-10-01 | — | — | US | claimed |
| EP-2900632-B1 | PREPARATION OF AN INTERMEDIATE COMPOUND OF IOFORMINOL | GE HEALTHCARE AS (NO) | 2019-10-30 | — | — | EP | disclosed |
| EP-2917174-B1 | PREPARATION OF INTERMEDIATES OF X-RAY CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2018-09-12 | — | — | EP | disclosed |
| US-9938233-B2 | Purification of X-ray contrast agents | GE HEALTHCARE AS (NO) | 2018-04-10 | — | — | US | disclosed |
| US-9884808-B2 | Preparation of an intermediate compound of ioforminol | GE HEALTHCARE AS (NO) | 2018-02-06 | — | — | US | disclosed |
| US-9827334-B2 | Preparation of ioforminol, an x-ray contrast agent | GE HEALTHCARE AS (NO) | 2017-11-28 | — | — | US | disclosed |
| US-9738596-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2017-08-22 | — | — | US | disclosed |
| US-20160304440-A1 | PURIFICATION OF X-RAY CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2016-10-20 | — | — | US | disclosed |
| US-9403757-B2 | Preparation of intermediates of X-ray contrast agents | GE HEALTHCARE AS (NO) | 2016-08-02 | — | — | US | disclosed |
| US-20110256068-A1 | CONTRAST MEDIA COMPOSITIONS | GE HEALTHCARE AS (NO) | 2011-10-20 | — | — | US | disclosed |
| US-D647037-S1 | Tire tread | LO TSAI JEN | 2011-10-18 | — | — | US | disclosed |
| US-20100322868-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2010-12-23 | — | — | US | disclosed |
| WO-2010079201-A1 | CONTRAST MEDIA COMPOSITIONS | GE HEALTHCARE AS (NO) | 2010-07-15 | — | — | WO | disclosed |
| EP-2178568-A2 | CONTRAST AGENTS | GE Healthcare AS (NO) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009008734-A2 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2009-01-15 | — | — | WO | disclosed |
| EP-0855997-A4 | FORMYL DERIVATIVES AS NONIONIC CONTRAST MEDIA | BIOPHYSICA INC (US) | 1998-10-07 | — | — | EP | disclosed |
| EP-0855997-A1 | FORMYL DERIVATIVES AS NONIONIC CONTRAST MEDIA | BIOPHYSICA, INC. (US) | 1998-08-05 | — | — | EP | disclosed |
| WO-1997000240-A1 | FORMYL DERIVATIVES AS NONIONIC CONTRAST MEDIA | BIOPHYSICA FOUNDATION (US) | 1997-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304440-A1 | PURIFICATION OF X-RAY CONTRAST AGENTS | TMEM97, OGFR, TMEM120A | LMNA 721/4885CYP2C19 3870/4885HIF1A 1865/4885 |
| US-20150274645-A1 | PREPARATION OF INTERMEDIATES OF X-RAY CONTRAST AGENTS | NAF1, NAA15, NAAA | LMNA 486/4885CYP2C19 2574/4885HIF1A 876/4885 |
| US-20110256068-A1 | CONTRAST MEDIA COMPOSITIONS | FPR1, FPR3, TPO | LMNA 2641/4885CYP2C19 4295/4885HIF1A 1948/4885 |
| US-20100322868-A1 | CONTRAST AGENTS | SSTR3, INSR, INSRR | LMNA 1656/4885CYP2C19 3523/4885HIF1A 1391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.