Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 6/20 | 0.42 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR1F | P30939 | 1/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7001519 | 0.83 | P4HTM (0.40) | P4HTMP4HA1MIFALDH1A1APLNR | |
| SCHEMBL15440496 | 0.82 | P4HTM (0.42) | P4HTMP4HA1MIFALDH1A1APLNR | |
| SCHEMBL30449388 | 0.82 | P4HTM (0.59) | P4HTMP4HA1MIFALDH1A1SMN1; SMN2 | |
| SCHEMBL110129 | 0.82 | P4HTM (0.59) | P4HTMP4HA1MIFALDH1A1SMN1; SMN2 | |
| SCHEMBL30074643 | 0.80 | KMT2A (0.58) | P4HTMALDH1A1APLNRKDM4EKMT2A | |
| SCHEMBL319254 | 0.80 | KMT2A (0.58) | P4HTMALDH1A1APLNRKDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL5223155 | 0.80 | P4HTM (0.57) | P4HTMP4HA1MIFALDH1A1SMN1; SMN2 | |
| SCHEMBL589084 | 0.80 | ALDH1A1 (0.47) | P4HTMP4HA1MIFALDH1A1APLNR | |
| SCHEMBL4860208 | 0.80 | P4HTM (0.41) | P4HTMP4HA1MIFALDH1A1APLNR | |
| SCHEMBL31474565 | 0.80 | P4HTM (0.57) | P4HTMP4HA1MIFALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016008582-A1 | SUBSTITUTED AZASPIRO(4.5)DECANE DERIVATIVES | Grünenthal GmbH (DE) | 2016-01-21 | — | — | WO | disclosed |