Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | MC3R | P41968 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL319254 | 1.00 | KMT2A (0.58) | KMT2ASIRT6ADORA3TSHRMC4R | |
| Hydrochloric Acid SCHEMBL4126365 | 0.98 | KMT2A (0.56) | KMT2ASIRT6ADORA3TSHRMC4R | |
| Formic Acid SCHEMBL2588798 | 0.92 | KMT2A (0.51) | KMT2ASIRT6ADORA3TSHRMC4R | |
| SCHEMBL25412159 | 0.92 | KMT2A (0.51) | KMT2ASIRT6ADORA3TSHRMC4R | |
| Butyramide SCHEMBL27726780 | 0.85 | KMT2A (0.45) | KMT2ASIRT6TSHRNAMPTP4HTM | |
| SCHEMBL25413661 | 0.85 | KMT2A (0.45) | KMT2ASIRT6NAMPTP4HTMJAK2 | |
| SCHEMBL27961477 | 0.84 | KMT2A (0.51) | KMT2AFLT3GRM2GSK3B | |
| SCHEMBL110129 | 0.80 | P4HTM (0.59) | KMT2ATSHRP4HTMKDM4EALDH1A1 | |
| SCHEMBL17447442 | 0.80 | P4HTM (0.42) | KMT2AP4HTMAPLNRKDM4EALDH1A1 | |
| SCHEMBL30449388 | 0.80 | P4HTM (0.59) | KMT2ATSHRP4HTMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11504439-B2 | Radioactive compound for diagnosis of malignant melanoma and use thereof | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2022-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11504439-B2 | Radioactive compound for diagnosis of malignant melanoma and use thereof | MITF, BRAF, MEN1 | KMT2A 1254/4885SIRT6 1910/4885ADORA3 1475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.