Sugi Predict

Sugi Predict / Compounds / SCHEMBL17448391

SCHEMBL17448391

SCHEMBL17448391

Cc1sc(I)c2ccccc12

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 3/20 0.38
▸ GPR3 P46089 1/20 0.36
▸ ALDH1A1 P00352 2/20 0.33
▸ CYP2A6 P11509 3/20 0.32
▸ TSHR P16473 2/20 0.30
▸ ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL120570 0.81 CYP1A2 (0.47) CYP1A2GPR3ALDH1A1CYP2A6TSHR
SCHEMBL18499842 0.81 GPR3 (0.45) CYP1A2GPR3ALDH1A1CYP2A6TSHR
SCHEMBL13780496 0.74 CYP1A2 (0.41) CYP1A2GPR3ALDH1A1CYP2A6TSHR
SCHEMBL14584177 0.70 CYP1A2 (0.38) CYP1A2GPR3ALDH1A1CYP2A6
SCHEMBL9310785 0.67 GPR3 (0.50) CYP1A2GPR3ALDH1A1TSHR
SCHEMBL10315962 0.67 CYP1A2 (0.35) CYP1A2GPR3ALDH1A1CYP2A6
SCHEMBL16900681 0.67 GPR3 (0.50) GPR3ALDH1A1
SCHEMBL14064326 0.67 CYP1A2 (0.35) CYP1A2GPR3ALDH1A1CYP2A6
SCHEMBL3005731 0.65 ALDH1A1 (0.37) CYP1A2GPR3ALDH1A1CYP2A6TSHR
SCHEMBL19214703 0.65 MAPT (0.33) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220199907-A1 PHOTODIODE Raynergy Tek Incorporation (TW) 2022-06-23 — — US disclosed
WO-2016009231-A1 NANOPARTICLES THE UNIVERSITY OF MANCHESTER (GB) 2016-01-21 — — WO disclosed