Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | STAT6 | P42226 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KRAS | P01116 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.43 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8267947 | 0.82 | KMT2A (0.49) | ALDH1A1KDM4EHPGDKMT2AHTR1A | |
| SCHEMBL5509239 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDKMT2AHTR1A | |
| SCHEMBL16052805 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDKMT2AHTR1A | |
| SCHEMBL8637983 | 0.73 | ALDH1A1 (0.72) | ALDH1A1KDM4EHPGDHTR1AHSD17B10 | |
| SCHEMBL8637989 | 0.73 | ALDH1A1 (0.72) | ALDH1A1KDM4EHPGDHTR1AHSD17B10 | |
| SCHEMBL2743907 | 0.70 | ALDH1A1 (0.77) | ALDH1A1KDM4EHPGDHTR1AHSD17B10 | |
| SCHEMBL2743909 | 0.70 | ALDH1A1 (0.77) | ALDH1A1KDM4EHPGDHTR1AHSD17B10 | |
| SCHEMBL17448620 | 0.69 | HDAC3 (0.42) | ALDH1A1HPGDKMT2AHTTMEN1 | |
| SCHEMBL17447204 | 0.68 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDKMT2AHTR1A | |
| SCHEMBL6106506 | 0.68 | ALDH1A1 (0.74) | ALDH1A1KDM4EHPGDHTR1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160016860-A1 | METHODS FOR PHOSPHINE OXIDE REDUCTION IN CATALYTIC WITTIG REACTIONS | DUBLIN CITY UNIVERSITY (IE) | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016860-A1 | METHODS FOR PHOSPHINE OXIDE REDUCTION IN CATALYTIC WITTIG REACTIONS | DCXR, TECR, PWWP2B | ALDH1A1 4341/4885KDM4E 361/4885HPGD 1231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.