Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.37 |
| ▸ | ELANE | P08246 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1094722 | 0.81 | SCN9A (0.46) | PLAUELANEFFAR1MET | |
| SCHEMBL1094641 | 0.80 | CA1 (0.44) | KMO | |
| SCHEMBL2821693 | 0.75 | ACMSD (0.42) | PLAUELANE | |
| SCHEMBL28710155 | 0.69 | BCL2L1 (0.46) | PLAUELANEF2KLKB1EGLN1 | |
| SCHEMBL28700571 | 0.69 | MAP4K4 (0.50) | PLAUELANEF2KLKB1EGLN1 | |
| SCHEMBL28705422 | 0.68 | EGLN1 (0.50) | EGLN1KMO | |
| SCHEMBL28710160 | 0.68 | KMO (0.42) | EGLN1KMO | |
| SCHEMBL15231450 | 0.68 | S1PR1 (0.37) | PLAUELANEFFAR1KMO | |
| SCHEMBL28696544 | 0.66 | CREBBP (0.40) | PLAUELANEEGLN1 | |
| SCHEMBL28712265 | 0.66 | ORAI1 (0.38) | PLAUELANEALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385938-A1 | SULFONAMIDE DERIVATIVES | Pfizer Limited (GB) | 2011-11-16 | — | — | EP | disclosed |
| US-8040476-B2 | Display device and method of producing the same | MITSUBISHI ELECTRIC CORPORATION (JP) | 2011-10-18 | — | — | US | disclosed |
| WO-2010079443-A1 | SULFONAMIDE DERIVATIVES | PFIZER LIMITED (GB) | 2010-07-15 | — | — | WO | disclosed |