SCHEMBL17448776

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17448774	0.83	KDM4E (0.43)	LMNAMAPTTRPA1CHRM1SLC6A2
	SCHEMBL5669450	0.80	SMN1; SMN2 (0.39)	LMNAMAPTTRPA1CHRM1SLC6A2
	SCHEMBL14887945	0.80	IDO1 (0.40)	AGXTIDO1CA1CA2CA9
	SCHEMBL8750365	0.75	TRPA1 (0.43)	LMNATRPA1CHRM1SLC6A2ADRA1A
	SCHEMBL8750414	0.74	TRPA1 (0.42)	LMNATRPA1CHRM1SLC6A2ADRA1A
	SCHEMBL29599465	0.73	AGXT (0.54)	AGXTIDO1CA1CA2CA9
	SCHEMBL407132	0.73	AGXT (0.54)	AGXTIDO1CA1CA2CA9
	SCHEMBL11786210	0.72	TRPA1 (0.45)	LMNATRPA1CHRM1SLC6A2ADRA1A
	SCHEMBL9073224	0.72	TRPA1 (0.41)	LMNATRPA1CHRM1SLC6A2ADRA1A
	SCHEMBL11230641	0.72	AGXT (0.48)	AGXTIDO1CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.