Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17448776 | 0.83 | AGXT (0.41) | KDM4EALDH1A1SLC6A2TRPA1LMNA | |
| SCHEMBL5669450 | 0.80 | SMN1; SMN2 (0.39) | KDM4EALDH1A1SLC6A2TRPA1LMNA | |
| SCHEMBL14887942 | 0.80 | KDM4E (0.38) | KDM4EALDH1A1SLC6A2PYCR1SRC | |
| SCHEMBL9070286 | 0.77 | KDM4E (0.44) | KDM4EALDH1A1SLC6A2PYCR1MEN1 | |
| SCHEMBL683175 | 0.77 | KDM4E (0.47) | KDM4EALDH1A1SLC6A2PYCR1MEN1 | |
| SCHEMBL8750365 | 0.75 | TRPA1 (0.43) | KDM4EALDH1A1SLC6A2TRPA1LMNA | |
| SCHEMBL8750414 | 0.74 | TRPA1 (0.42) | KDM4EALDH1A1SLC6A2TRPA1LMNA | |
| SCHEMBL30618212 | 0.73 | ALDH1A1 (0.44) | KDM4EALDH1A1SLC6A2LMNAPYCR1 | |
| SCHEMBL8516081 | 0.73 | ALDH1A1 (0.44) | KDM4EALDH1A1SLC6A2LMNAPYCR1 | |
| SCHEMBL15012476 | 0.73 | ALDH1A1 (0.44) | KDM4EALDH1A1LMNAPYCR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160015707-A1 | METHOD OF PROMOTING REMYELINATION | UNIV CASE WESTERN RESERVE (US) | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160015707-A1 | METHOD OF PROMOTING REMYELINATION | CHAT, PMP22, MAG | KDM4E 1491/4885ALDH1A1 761/4885SLC6A2 1827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.