Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | DUT | P33316 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17449425 | 0.81 | IRAK4 (0.36) | IRAK4HTR7 | |
| SCHEMBL17440700 | 0.78 | IRAK4 (0.35) | IRAK4DUT | |
| SCHEMBL17440633 | 0.77 | IRAK4 (0.33) | IRAK4 | |
| SCHEMBL17440632 | 0.77 | IRAK4 (0.33) | IRAK4 | |
| SCHEMBL3509158 | 0.76 | IRAK4 (0.34) | IRAK4HTR7 | |
| SCHEMBL17449172 | 0.76 | MAPT (0.39) | IRAK4 | |
| SCHEMBL24742213 | 0.74 | HTR7 (0.54) | DUTHTR7 | |
| SCHEMBL29987682 | 0.74 | HTR7 (0.54) | DUTHTR7 | |
| SCHEMBL28700862 | 0.73 | HTR2A (0.32) | IRAK4 | |
| SCHEMBL4841304 | 0.73 | ADRB1 (0.38) | IRAK4HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016011390-A1 | IRAK4 INHIBITING AGENTS | BIOGEN MA INC. (US) | 2016-01-21 | — | — | WO | disclosed |