Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12440112 | 0.97 | MEN1 (0.50) | MEN1KMT2APSMB5ALDH1A1MCL1 | |
| SCHEMBL22064537 | 0.82 | CA1 (0.38) | ALDH1A1MCL1LMNARECQLPRMT3 | |
| SCHEMBL16802010 | 0.82 | KMT2A (0.50) | MEN1KMT2APSMB5ALDH1A1MCL1 | |
| SCHEMBL20960533 | 0.82 | KMT2A (0.50) | MEN1KMT2APSMB5ALDH1A1MCL1 | |
| SCHEMBL1463416 | 0.82 | CA1 (0.38) | ALDH1A1MCL1LMNARECQLPRMT3 | |
| SCHEMBL24080628 | 0.81 | CASP2 (0.47) | PSMB5LMNAGAARECQL | |
| SCHEMBL24080619 | 0.81 | CASP2 (0.47) | PSMB5LMNAGAARECQL | |
| SCHEMBL31758445 | 0.81 | CASP2 (0.47) | PSMB5LMNAGAARECQL | |
| SCHEMBL23289286 | 0.80 | MEN1 (0.48) | MEN1KMT2APSMB5ALDH1A1MCL1 | |
| SCHEMBL23471380 | 0.80 | MEN1 (0.48) | MEN1KMT2APSMB5ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2809660-B1 | MACROCYCLIC COMPOUNDS FOR MODULATING IL-17 | ENSEMBLE THERAPEUTICS CORP (US) | 2016-01-20 | — | — | EP | disclosed |
| US-20150118760-A1 | FLUORESCENT SENSING OF VAPORS USING TUBULAR NANOFIBRIL MATERIALS | UNIVERSITY OF UTAH RESEARCH FOUNDATION | 2015-04-30 | — | — | US | disclosed |