Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24080619 | 1.00 | CASP2 (0.47) | CASP2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL31758445 | 1.00 | CASP2 (0.47) | CASP2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL16307753 | 0.98 | CASP2 (0.48) | CASP2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL29756956 | 0.85 | FAAH (0.59) | CASP2PSMB5FAAHRECQLGAA | |
| SCHEMBL23718659 | 0.85 | FAAH (0.59) | CASP2PSMB5FAAHRECQLGAA | |
| SCHEMBL17676463 | 0.84 | FAAH (0.56) | CASP2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL31758434 | 0.83 | CASP2 (0.59) | CASP2FAAH | |
| SCHEMBL24376199 | 0.82 | CASP2 (0.47) | CASP2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL30207060 | 0.82 | FAAH (0.51) | CASP2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL27034830 | 0.82 | FAAH (0.51) | CASP2HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11191845-B2 | CD38 antibody drug conjugate | SORRENTO THERAPEUTICS, INC. (US) | 2021-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11191845-B2 | CD38 antibody drug conjugate | CD38, CD22, CD2 | CASP2 4052/4885HDAC3 980/4885HDAC1 1927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.