Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | PPARG | P37231 | 8/20 | 0.53 |
| ▸ | PPARA | Q07869 | 8/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.53 |
| ▸ | PTGES | O14684 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473308 | 0.88 | AKR1C3 (0.57) | HTTPPARGPPARAALOX5ALDH1A1 | |
| SCHEMBL7345917 | 0.84 | PPARG (0.72) | PPARGPPARAALOX5PTGES | |
| SCHEMBL6934157 | 0.84 | LMNA (0.55) | HTTPPARGPPARAALOX5PTGES | |
| SCHEMBL6930527 | 0.83 | PPARG (0.67) | PPARGPPARAALOX5PTGES | |
| SCHEMBL6935114 | 0.82 | PPARG (0.65) | PPARGPPARAALOX5PTGESMMP9 | |
| SCHEMBL728315 | 0.81 | ALDH1A1 (0.71) | HTTPPARGPPARAALOX5POLB | |
| SCHEMBL1747654 | 0.81 | HTT (0.72) | HTTPPARGPPARAALOX5PTGES | |
| SCHEMBL19501967 | 0.81 | HTT (0.72) | HTTPPARGPPARAALOX5PTGES | |
| SCHEMBL1931269 | 0.80 | HTT (0.71) | HTTPPARGPPARAALOX5PTGES | |
| SCHEMBL9099120 | 0.80 | HTT (0.71) | HTTPPARGPPARAALOX5PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385032-A1 | GPR40 Receptor function regulator | Takeda Pharmaceutical Company Limited (JP) | 2011-11-09 | — | — | EP | disclosed |
| US-7960369-B2 | Receptor function regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-06-14 | — | — | US | disclosed |