Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1745002 | 0.73 | GABRA1 (0.39) | CA12CA9GABRA1GABRB2AURKA | |
| SCHEMBL17045728 | 0.68 | CDK4 (0.37) | PARP1 | |
| SCHEMBL11792710 | 0.67 | TRPM4 (0.42) | GABRA1GABRB2AURKAKDR | |
| SCHEMBL458515 | 0.67 | CA12 (0.44) | CA12CA9AURKAKDRPARP1 | |
| SCHEMBL5138488 | 0.65 | HTR2A (0.42) | GABRA1GABRB2AURKAKDR | |
| SCHEMBL10522918 | 0.65 | GABRA1 (0.43) | GABRA1GABRB2AKR1B1 | |
| SCHEMBL28193331 | 0.64 | AURKA (0.38) | GABRA1GABRB2AURKAKDRAKR1B1 | |
| SCHEMBL7195961 | 0.64 | MEN1 (0.43) | GABRA1GABRB2AURKAKDR | |
| SCHEMBL21175462 | 0.64 | GABRA1 (0.46) | GABRA1GABRB2AKR1B1 | |
| SCHEMBL17108092 | 0.62 | CA12 (0.43) | CA12CA9AURKAKDRPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2387564-A1 | BENZO ÝC¨PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | Rutgers, The State University of New Jersey (US) | 2011-11-23 | — | — | EP | disclosed |
| US-8037884-B2 | Modular system for patient positioning during medical procedures | ALLEN MEDICAL SYSTEMS, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| WO-2010083436-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-07-22 | — | — | WO | disclosed |