Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1745000 | 0.73 | CA12 (0.33) | GABRA1GABRB2CA12CA9ADRA1D | |
| SCHEMBL5831594 | 0.71 | GABRA1 (0.56) | GABRA1GABRB2LMNAHTTKDM4E | |
| SCHEMBL31619949 | 0.71 | GABRA1 (0.56) | GABRA1GABRB2LMNAHTTKDM4E | |
| SCHEMBL458515 | 0.70 | CA12 (0.44) | CA12CA9LMNAHTTKDM4E | |
| SCHEMBL16487340 | 0.67 | GABRA1 (0.46) | GABRA1GABRB2LMNAKDM4ECYP1A2 | |
| SCHEMBL30083977 | 0.67 | GABRA1 (0.46) | GABRA1GABRB2LMNAKDM4ECYP1A2 | |
| SCHEMBL5831736 | 0.67 | GABRA1 (0.45) | GABRA1GABRB2LMNAHTTKDM4E | |
| SCHEMBL252161 | 0.66 | PNMT (0.62) | GABRA1GABRB2ADRA1DADRA1AADRA1B | |
| SCHEMBL1147979 | 0.66 | HPRT1 (0.52) | GABRA1GABRB2LMNACYP1A2CYP2D6 | |
| SCHEMBL30083974 | 0.66 | HPRT1 (0.52) | GABRA1GABRB2LMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2387564-A1 | BENZO ÝC¨PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | Rutgers, The State University of New Jersey (US) | 2011-11-23 | — | — | EP | disclosed |
| US-8037884-B2 | Modular system for patient positioning during medical procedures | ALLEN MEDICAL SYSTEMS, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| WO-2010083436-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-07-22 | — | — | WO | disclosed |