Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17450539 | 0.87 | ACE (0.45) | LMNAACEOPRM1OPRD1OPRK1 | |
| SCHEMBL17450514 | 0.86 | ACE (0.44) | LMNAACEOPRM1OPRD1OPRK1 | |
| SCHEMBL17450537 | 0.83 | PRCP (0.43) | LMNAACESMN1; SMN2 | |
| SCHEMBL29638229 | 0.81 | CMA1 (0.43) | OPRM1OPRD1OPRK1 | |
| SCHEMBL17450538 | 0.75 | CTSC (0.44) | KIF11 | |
| SCHEMBL29777557 | 0.73 | F2 (0.48) | ACEOPRM1OPRD1 | |
| SCHEMBL18736930 | 0.73 | KIF11 (0.48) | KIF11 | |
| SCHEMBL30597004 | 0.73 | ACE (0.58) | LMNAACE | |
| SCHEMBL8127147 | 0.73 | KIF11 (0.67) | KIF11 | |
| SCHEMBL9135894 | 0.73 | KIF11 (0.67) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016009341-A1 | THIOREDOXIN MIMETIC PRODRUGS AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2016-01-21 | — | — | WO | disclosed |