SCHEMBL8127147

SCHEMBL8127147

CCOC(=O)[C@@H](N)CSC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 19/20 0.67
DNMT1 P26358 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9135894 1.00 KIF11 (0.67) KIF11DNMT1
SCHEMBL3439368 0.87 KIF11 (0.85) KIF11DNMT1
SCHEMBL9137501 0.87 KIF11 (0.85) KIF11DNMT1
SCHEMBL12872399 0.87 KIF11 (0.85) KIF11DNMT1
SCHEMBL15662531 0.85 KIF11 (0.70) KIF11DNMT1
Hydrochloric Acid SCHEMBL29401160 0.85 KIF11 (0.82) KIF11DNMT1
Hydrochloric Acid SCHEMBL13736621 0.85 KIF11 (0.82) KIF11DNMT1
SCHEMBL7554607 0.85 KIF11 (0.61) KIF11DNMT1
SCHEMBL5996941 0.84 KIF11 (0.65) KIF11DNMT1
SCHEMBL29635035 0.84 KIF11 (0.65) KIF11DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016009341-A1 THIOREDOXIN MIMETIC PRODRUGS AND USES THEREOF RADIKAL THERAPEUTICS INC. (US) 2016-01-21 WO disclosed
EP-0692982-B1 RADIOLABELED PLATELET GPIIb/IIIa RECEPTOR ANTAGONISTS AS IMAGING AGENTS FOR THE DIAGNOSIS OF THROMBOEMBOLIC DISORDERS DU PONT PHARM CO (US) 2000-07-05 EP disclosed
EP-0995761-A2 Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders Dupont Pharmaceuticals Company (US) 2000-04-26 EP disclosed
US-6022523-A NOVEL CYCLIC COMPOUNDS CONTAINING CARBOCYCLIC AND HETEROCYCLIC RING SYSTEMS DUPONT PHARMACEUTICALS COMPANY (US) 2000-02-08 US disclosed
US-5879657-A Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1999-03-09 US disclosed
EP-0692982-A4 RADIOLABELED PLATELET GPIIb/IIIa RECEPTOR ANTAGONISTS AS IMAGING AGENTS FOR THE DIAGNOSIS OF THROMBOEMBOLIC DISORDERS DU PONT MERCK PHARMA (US) 1998-03-11 EP disclosed
EP-0575273-B1 Crosslinkable derivatives of collagen, process for obtaining the same and their use in the preparation of biomaterials FLAMEL TECH SA (FR) 1997-12-03 EP disclosed
EP-0692982-A1 RADIOLABELED PLATELET GPIIb/IIIa RECEPTOR ANTAGONISTS AS IMAGING AGENTS FOR THE DIAGNOSIS OF THROMBOEMBOLIC DISORDERS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-01-24 EP disclosed
US-5412076-A Crosslinkable collagen derivatives, process for their production and their application to the preparation of biomaterials FLAMEL TECHNOLOGIES (FR) 1995-05-02 US disclosed
WO-1994022494-A1 RADIOLABELED PLATELET GPIIb/IIIa RECEPTOR ANTAGONISTS AS IMAGING AGENTS FOR THE DIAGNOSIS OF THROMBOEMBOLIC DISORDERS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1994-10-13 WO disclosed
EP-0575273-A1 Crosslinkable derivatives of collagen, process for obtaining the same and their use in the preparation of biomaterials FLAMEL TECHNOLOGIES, Société Anonyme (FR) 1993-12-22 EP disclosed