SCHEMBL17451128

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17451133	0.98	KMT2A (0.50)	KMT2AADORA1HSP90AA1DNM1RAB9A
	SCHEMBL31374318	0.97	KMT2A (0.49)	KMT2AADORA1HSP90AA1DNM1RAB9A
	SCHEMBL7237360	0.93	ADORA1 (0.54)	KMT2AADORA1RAB9AMEN1POLB
	SCHEMBL13227316	0.91	KMT2A (0.55)	KMT2AADORA1HSP90AA1RAB9AMEN1
	SCHEMBL9564261	0.89	KMT2A (0.57)	KMT2AADORA1HSP90AA1RAB9AMEN1
	SCHEMBL10345111	0.89	KMT2A (0.42)	KMT2AADORA1DNM1RAB9AMEN1
	SCHEMBL28757288	0.88	SOAT1 (0.56)	KMT2AMEN1FAAH
	SCHEMBL17451137	0.86	ADORA1 (0.51)	ADORA1ALDH1A1MAPTCA1CA2
	SCHEMBL20072339	0.86	HDAC3 (0.42)	KMT2AADORA1RAB9AMEN1POLB
	SCHEMBL6579026	0.83	KMT2A (0.41)	KMT2AADORA1DNM1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.