Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13227316 | 0.98 | KMT2A (0.55) | KMT2AADORA1HSP90AA1NPC1RAB9A | |
| SCHEMBL17451133 | 0.91 | KMT2A (0.50) | KMT2AADORA1HSP90AA1NPC1RAB9A | |
| SCHEMBL17451128 | 0.89 | KMT2A (0.49) | KMT2AADORA1HSP90AA1NPC1RAB9A | |
| SCHEMBL27864381 | 0.87 | KMT2A (0.50) | KMT2AADORA1HSP90AA1NPC1RAB9A | |
| SCHEMBL31403451 | 0.86 | KMT2A (0.49) | KMT2AADORA1HSP90AA1NPC1RAB9A | |
| SCHEMBL31374318 | 0.86 | KMT2A (0.49) | KMT2AADORA1HSP90AA1NPC1RAB9A | |
| SCHEMBL7237360 | 0.85 | ADORA1 (0.54) | KMT2AADORA1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9564243 | 0.85 | ADORA1 (0.59) | KMT2AADORA1NPC1RAB9ASMN1; SMN2 | |
| Potassium SCHEMBL31403450 | 0.84 | KMT2A (0.48) | KMT2AADORA1HSP90AA1NPC1RAB9A | |
| SCHEMBL22610228 | 0.81 | LMNA (0.58) | KMT2AADORA1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9238752-B2 | Bituminous composition with thermoreversible properties | TOTAL RAFFINAGE MARKETING (FR) | 2016-01-19 | — | — | US | disclosed |
| US-20130298800-A1 | BITUMINOUS COMPOSITION WITH THERMOREVERSIBLE PROPERTIES | TOTALENERGIES ONETECH (FR) | 2013-11-14 | — | — | US | disclosed |
| US-20100192804-A1 | BITUMINOUS COMPOSITION WITH THERMOREVERSIBLE PROPERTIES | TOTAL RAFFINAGE MARKETING (FR) | 2010-08-05 | — | — | US | disclosed |
| EP-0541966-A2 | Process for preparing amide derivatives from halomines and acid halides | AMERICAN CYANAMID COMPANY (US) | 1993-05-19 | — | — | EP | disclosed |