SCHEMBL17451237

SCHEMBL17451237

COC(=O)CC(C)c1ccc2ccccc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UGT2B7 P16662 1/20 0.50
ABCB11 O95342 1/20 0.50
ALDH1A1 P00352 1/20 0.49
MMP9 P14780 1/20 0.49
RAB9A P51151 2/20 0.48
MAPT P10636 1/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
CYP1A2 P05177 2/20 0.48
TSHR P16473 2/20 0.48
CYP2D6 P10635 1/20 0.48
HIF1A Q16665 1/20 0.48
RECQL P46063 1/20 0.47
GAA P10253 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TNF P01375 1/20 0.46
PTGS1 P23219 2/20 0.45
PTGS2 P35354 2/20 0.45
AKR1C3 P42330 2/20 0.45
AKR1C2 P52895 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14349888 0.88 ABCB11 (0.67) ABCB11MAPTCYP1A2TSHRPTGS1
SCHEMBL12320564 0.86 SLC6A2 (0.50) UGT2B7MMP9CYP2D6TNF
SCHEMBL12430383 0.85 GAA (0.55) UGT2B7ABCB11ALDH1A1MMP9MEN1
SCHEMBL22076569 0.84 CYP2D6 (0.55) UGT2B7MMP9RAB9AMAPTMEN1
SCHEMBL2294505 0.83 TNF (0.45) UGT2B7MMP9RAB9AMAPTMEN1
SCHEMBL2203728 0.82 FFAR1 (0.57) UGT2B7MMP9RAB9AMEN1KMT2A
Hydrochloric Acid SCHEMBL6778876 0.82 TNF (0.44) UGT2B7MMP9RAB9AMAPTMEN1
SCHEMBL27989030 0.81 TNF (0.56) UGT2B7MMP9RAB9AMEN1KMT2A
SCHEMBL6172465 0.81 TNF (0.56) UGT2B7MMP9RAB9AMEN1KMT2A
SCHEMBL27980860 0.81 TNF (0.56) UGT2B7MMP9RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2977373-B1 METHOD FOR THE CATALYTIC PRODUCTION OF ESTERS EVONIK DEGUSSA GMBH (DE) 2017-10-25 EP disclosed
EP-3037402-B1 METHOD FOR THE ALKOXYCARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS EVONIK DEGUSSA GMBH (DE) 2017-05-17 EP disclosed
EP-3037402-B1 METHOD FOR THE ALKOXYCARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS EVONIK DEGUSSA GMBH (DE) 2017-05-17 EP disclosed
EP-3037402-A1 METHOD FOR THE ALKOXYCARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS Evonik Degussa GmbH (DE) 2016-06-29 EP disclosed
EP-3037402-A1 METHOD FOR THE ALKOXYCARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS Evonik Degussa GmbH (DE) 2016-06-29 EP disclosed
EP-2977373-A1 METHOD FOR THE CATALYTIC PRODUCTION OF ESTERS Evonik Degussa GmbH (DE) 2016-01-27 EP disclosed